2-(Methylthio)-6-phenyl-3-(m-tolyl)pyrimidin-4(3H)-one CAS 89069-48-7
| CAS No. | 89069-48-7 |
| Molecular Formula | C18H16N2OS |
| Molecular Weight | 308.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Methylthio)-6-phenyl-3-(m-tolyl)pyrimidin-4(3H)-one (CAS 89069-48-7) is a high-purity analytical reference standard with the molecular formula C18H16N2OS and a molecular weight of 308.40 g/mol.
The molecular framework of 2-(Methylthio)-6-phenyl-3-(m-tolyl)pyrimidin-4(3H)-one (C18H16N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16N2OS |
| Molecular Weight | 308.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- 2-(Methylthio)-6-phenyl-3-(o-tolyl)pyrimidin-4(3H)-one (CAS 89069-47-6)
- 2-(Methylthio)-6-phenyl-3-(p-tolyl)pyrimidin-4(3H)-one (CAS 89069-49-8)
- 3-(4-(Methylthio)phenyl)-1-(p-tolyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-90-1)
- N-(2-(6-(Methylthio)-4-(propylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)acetamide (CAS 946282-08-2)
- N-(2-(Methylthio)benzo[d]thiazol-6-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide (CAS 864937-53-1)
- 2-(Methylthio)-N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-4-yl)acetamide (CAS 2246709-52-2)
- (6-Methyl-3-(methylthio)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl 3-fluorobenzoate (CAS 877642-76-7)
- 4-(4-(Methylthio)phenyl)-1,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazin-2-amine (CAS 452285-32-4)
Recommended Standards
- 2-((2-Phenoxyethyl)thio)-1-(prop-2-yn-1-yl)-1H-benzo[d]imidazole (CAS 920115-68-0)
- 1-Methyl-3-phenyl-5-(p-tolylthio)-1H-pyrazole-4-carbaldehyde (CAS 318233-98-6)
- 1-Benzyl-2-(benzylthio)pyrimidin-4(1H)-one (CAS 6146-26-5)
- 2-(Tert-butyl)-3-formyl-N,N-dimethyl-1H-indole-5-sulfonamide (CAS 591204-93-2)
- 1-(2-(Prop-2-yn-1-yloxy)phenyl)-1H-imidazole (CAS 61292-54-4)
- 1-(3-fluoro-4-methoxybenzyl)piperazine (CAS 523980-18-9)
- 2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid (CAS 134795-25-8)
- 3-Formyl-5-hydroxy-N-methylbenzamide (CAS 1243439-76-0)
- tert-Butyl (2-bromo-6-chloro-4-fluorophenyl)carbamate (CAS 1879205-70-5)
- (1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-4-yl)methanamine hydrochloride (CAS 1420802-63-6)
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- 2,5-Dichloroaniline-3,4,6-d3 (CAS 783321-80-2)
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