1-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)-3-(furan-2-ylmethyl)urea CAS 891104-82-8
| CAS No. | 891104-82-8 |
| Molecular Formula | C16H16FN3O3 |
| Molecular Weight | 317.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)-3-(furan-2-ylmethyl)urea is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)-3-(furan-2-ylmethyl)urea (CAS 891104-82-8), a certified reference material (molecular formula C16H16FN3O3, MW 317.31 g/mol) for analytical method development and quality control.
The molecular framework of 1-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)-3-(furan-2-ylmethyl)urea (C16H16FN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)-3-(furan-2-ylmethyl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16FN3O3 |
| Molecular Weight | 317.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 1-[1-(4-Fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]piperidine-4-carboxylic acid (CAS 1171184-76-1)
- 1-(4-(2-Fluorophenyl)-3-oxo-3,4-dihydropyrazin-2-yl)piperidine-4-carboxylic acid (CAS 1707603-27-7)
- 1-(4-(3-Fluorophenyl)-3-oxo-3,4-dihydropyrazin-2-yl)piperidine-3-carboxylic acid (CAS 1713590-12-5)
- 1-(1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl)-3-(furan-2-ylmethyl)urea (CAS 891106-63-1)
- (E)-2-(2-Fluorophenyl)-3-[3-(2-pyrimidinyloxy)phenyl]-2-propenenitrile (CAS 861210-17-5)
- 8-(4-Fluorophenyl)-4-oxo-N-propyl-4,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3-carboxamide (CAS 946311-93-9)
- (E)-3-((4-fluorophenyl)amino)-1-(4-(3-fluoropropoxy)phenyl)prop-2-en-1-one (CAS 477889-14-8)
- (3-(4-Fluorophenyl)-4-(2-(methylthio)pyrimidin-4-yl)isoxazol-5-yl)methanol (CAS 673451-64-4)
Recommended Standards
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid (CAS 49759-64-0)
- (R)-2-(((benzyloxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid (CAS 49759-66-2)
- 2-(((Benzyloxy)carbonyl)amino)-3-(2-fluorophenyl)propanoic acid (CAS 401-28-5)
- (E)-4-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-1,1,1-trifluorobut-3-en-2-one (CAS 478047-03-9)
- N-Methyl-2-(5-oxo-5,6-dihydro-4H-imidazo[1,2-b][1,2,4]triazol-6-yl)acetamide (CAS 1428139-10-9)
- 4,5-Dimethyl-2-(1h-pyrrol-1-yl)thiophene-3-carboxylic acid (CAS 26176-19-2)
- 1-Bromo-2-(difluoromethoxy)-3-iodobenzene (CAS 1261759-81-2)
- 3,7-Dimethyl-6-oxo-6,7-dihydroisoxazolo[5,4-b]pyridine-5-carbaldehyde (CAS 1352534-45-2)
- 1-(4-Methoxy-3,5-dimethylpyridin-2-yl)-N-methylmethanamine dihydrochloride (CAS 1158623-74-5)
- 3-(Trifluoromethyl)quinoline (CAS 25199-76-2)
- 2,4-Dichloro-N-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)-N-(4-methoxyphenyl)benzenesulfonamide (CAS 957041-78-0)
- X69NU20D19 7790-76-3 Calcium Pyrophosphate Calcium diphosphate Diphosphoric acid, calcium salt (1:2) Dicalcium pyrophosphate, with a fluorine content of less than 0,005 % by weight on the dry anhydrous product Dicalcium pyrophosphate Calcium phosphate (Ca2P2O7) alpha-Calcium pyrophosphate Calcium pyrophosphate (Ca2P2O7) Dicalcium diphosphate EINECS 232-221-5 HSDB 1435 Pyrophosphoric acid, calcium salt (1:2) UNII-X69NU20D19 EC 232-221-5 (CAS 7790-76-3)
- Tert-butyl (2-carbamimidoylphenyl)carbamate (CAS 1340558-17-9)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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