(2-Phenylthiazol-4-yl)methanamine dihydrochloride CAS 89152-61-4
| CAS No. | 89152-61-4 |
| Molecular Formula | C10H10N2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (2-Phenylthiazol-4-yl)methanamine dihydrochloride (CAS 89152-61-4), a certified reference material (molecular formula C10H10N2SHCl, MW 226.72 g/mol) for analytical method development and quality control.
The molecular framework of (2-Phenylthiazol-4-yl)methanamine dihydrochloride (C10H10N2SHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10N2S 2*HCl |
| Molecular Weight | 226.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Phenylthiazol Standards
- 1-(2-Phenylthiazol-5-yl)ethanone (CAS 10045-50-8)
- N-(4-Phenylthiazol-2-yl)hexanamide (CAS 100957-62-8)
- 2-(5-Methyl-2-phenylthiazol-4-yl)acetic acid (CAS 101736-22-5)
- 2-(2-Methyl-4-phenylthiazol-5-yl)ethan-1-amine (CAS 1017486-41-7)
- (2-Phenylthiazol-5-yl)methanamine hydrochloride (CAS 1047620-81-4)
- 6-(4-Methyl-2-phenylthiazol-5-yl)pyridazin-3-ol (CAS 1105195-28-5)
- 1-(2-Phenylthiazol-5-yl)ethan-1-amine hydrochloride (CAS 1196155-65-3)
- 1-(4-Methyl-2-phenylthiazol-5-yl)-3-(pyridin-3-yl)prop-2-en-1-one (CAS 1211941-77-3)
Recommended Standards
- 7,7-Dimethyl-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylic acid (CAS 1503608-57-8)
- methyl 2-amino-4,5,6,7-tetrahydro-1,3-benzothiazole-5-carboxylate (CAS 1909348-03-3)
- 2-{2-[(3-Chlorobenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1220031-54-8)
- 2,3,5-Trihydroxybenzoic acid (CAS 33580-60-8)
- 4-Bromo-2-(2-nitrovinyl)phenol (CAS 61131-72-4)
- 1-(2-Ethoxyphenyl)-1H-pyrrole-2-carbaldehyde (CAS 299164-56-0)
- 3-BRomo-4-oxo-1,4-dihydro-quinoline-6-carbonitrile (CAS 304904-69-6)
- decahydroisoquinolin-6-ol (CAS 725228-44-4)
- 1H-Pyrazolo[3,4-c]pyridine-5-carboxylic Acid (CAS 1256824-45-9)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
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