5'-Chloro-5'-deoxyadenosine CAS 892-48-8
| CAS No. | 892-48-8 |
| Molecular Formula | C10H12ClN5O3 |
| Molecular Weight | 285.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5'-Chloro-5'-deoxyadenosine (CAS 892-48-8) is a high-purity analytical reference standard with the molecular formula C10H12ClN5O3 and a molecular weight of 285.69 g/mol.
The molecular framework of 5'-Chloro-5'-deoxyadenosine (C10H12ClN5O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN5O3 |
| Molecular Weight | 285.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- 2-(4-(Chloromethyl)-1H-pyrazol-1-yl)pyridine hydrochloride (CAS 1449117-51-4)
- 4-Benzyloxybenzyl Bromide (CAS 5544-60-5)
- (R)-1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (CAS 62751-59-1)
- 2-[(3-Bromobenzyl)oxy]-5-chlorobenzoyl chloride (CAS 1160260-64-9)
- Ethanol, 2,2'-(pentadecylimino)bis- (CAS 24910-32-5)
- 3-Amino-N-benzyl-4-methoxybenzamide (CAS 101112-38-3)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
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