2-(Methylsulfonyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline CAS 892254-08-9
| CAS No. | 892254-08-9 |
| Molecular Formula | C10H11F3N2O2S |
| Molecular Weight | 280.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-(Methylsulfonyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2-(Methylsulfonyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline (CAS 892254-08-9), a certified reference material (molecular formula C10H11F3N2O2S, MW 280.27 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H11F3N2O2S, 2-(Methylsulfonyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 280.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11F3N2O2S |
| Molecular Weight | 280.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylsulfonyl Standards
- 7-[4-(Methylsulfonyl)phenyl]-5,8-diazaspiro[3.4]octan-6-one (CAS 1272755-84-6)
- 1'-(Methylsulfonyl)spiro[indoline-3,4'-piperidin]-2-one (CAS 1792177-22-0)
- 2-(1-(Methylsulfonyl)piperidin-4-yl)benzo[d]oxazole (CAS 605627-81-4)
- 1-{5-[4-(Methylsulfonyl)phenyl]-2-thienyl}ethanone (CAS 893741-75-8)
- 8-Benzyl-3-(methylsulfonyl)-3,8-diazabicyclo[3.2.1]Octane (CAS 2139492-02-5)
- 4-[3-(Methylsulfonyl)phenyl]-1-propyl-1,2,3,6-tetrahydropyridine (CAS 346688-39-9)
- N-(methylsulfonyl)-N-(naphthalen-1-yl)glycine (CAS 330967-96-9)
- 2-(3-(Methylsulfonyl)-5-phenyl-4H-1,2,4-triazol-4-yl)acetic acid (CAS 892874-30-5)
Recommended Standards
- 2-(Hydroxy(4-methoxyphenyl)methylene)-1H-indene-1,3(2H)-dione (CAS 860784-13-0)
- 2-[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]thiophene-3-carbonitrile (CAS 338777-54-1)
- 2-(4-Oxo-3-phenyl-4H-chromen-8-yl)acetic acid (CAS 87627-17-6)
- 2-[2-(2-fluorobenzamido)-1,3-thiazol-4-yl]acetic acid (CAS 926245-67-2)
- 5-(bromomethyl)-2-(trifluoromethyl)pyridine;hydrobromide (CAS 1263413-35-9)
- 2-(1-Amino-4-tert-Butylcyclohexyl)acetic acid (CAS 1339351-05-1)
- 3-Fluoro-4-trifluoromethylbenzoic acid (CAS 115754-21-7)
- Daprodustat Impurity 39 (CAS CATO-C4X-240739)
- Ilaprazole Impurity 75 (CAS 102625-98-9)
- 5-(1-Ethyl-2-oxoindolin-3-ylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 371212-46-3)
- Ethyl 2-(bromomethyl)-5-methoxybenzoate (CAS 867296-88-6)
- Diphenyl ((5-fluoro-6-methylpyridin-2-yl)(phenylamino)methyl)phosphonate (CAS 1132610-60-6)
- N'-(Furan-2-ylmethylene)-2-((4-methoxyphenyl)amino)acetohydrazide (CAS 303083-30-9)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com