3-(4-Chlorobenzoyl)-6-fluoroquinolin-4(1H)-one CAS 892281-06-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Chlorobenzoyl)-6-fluoroquinolin-4(1H)-one.

3-(4-Chlorobenzoyl)-6-fluoroquinolin-4(1H)-one (CAS 892281-06-0), molecular formula C16H9ClFNO2 and molecular weight 301.70 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C16H9ClFNO2, 3-(4-Chlorobenzoyl)-6-fluoroquinolin-4(1H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 301.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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