3-((4-Chlorophenyl)sulfonyl)-N-(4-isopropylphenyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine CAS 892738-90-8
| CAS No. | 892738-90-8 |
| Molecular Formula | C22H18ClN5O2S2 |
| Molecular Weight | 483.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-((4-Chlorophenyl)sulfonyl)-N-(4-isopropylphenyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine (CAS 892738-90-8), a certified reference material (molecular formula C22H18ClN5O2S2, MW 483.99 g/mol) for analytical method development and quality control.
The molecular framework of 3-((4-Chlorophenyl)sulfonyl)-N-(4-isopropylphenyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine (C22H18ClN5O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((4-Chlorophenyl)sulfonyl)-N-(4-isopropylphenyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H18ClN5O2S2 |
| Molecular Weight | 483.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 2-((6-(4-Chlorophenyl)-3-cyano-4-(p-tolyl)pyridin-2-yl)thio)-N-(m-tolyl)acetamide (CAS 444156-76-7)
- N-[(4-Chlorophenyl)methyl]-2-{[3-ethyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1040632-03-8)
- (2Z)-3-[4-(4-Chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]-2-[3-(trifluoromethyl)phenyl]prop-2-enenitrile (CAS 383147-93-1)
- Ethyl 5-(4-chlorophenyl)-7-methyl-2-(4-nitrobenzylidene)-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 300377-47-3)
- (E)-[(5-{[(2-chlorophenyl)methyl]sulfanyl}-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylidene]amino 4-methoxybenzoate (CAS 321553-41-7)
- (5-((4-Chlorophenyl)thio)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl (3-chlorophenyl)carbamate (CAS 318248-31-6)
- N-(2-chlorophenyl)-2-((5-(((4-chlorophenyl)amino)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332930-62-8)
- 1,6-Bis(2-chlorophenyl)-1,6-diphenylhexa-2,4-diyne-1,6-diol (CAS 96158-84-8)
Recommended Standards
- tert-Butyl (R)-3-(7-chloro-2-(2-methylisonicotinamido)-1H-benzo[d]imidazol-1-yl)azepane-1-carboxylate (CAS 1508258-34-1)
- (2S,4R)-Benzyl 4-amino-5-(5'-chloro-2'-fluoro-[1,1'-biphenyl]-4-yl)-2-(ethoxymethyl)-2-methylpentanoate (CAS 1562405-20-2)
- Metoclopramide Impurity 122 (CAS CATO-C4X-1415122)
- 3-(4-(2-(4-(5-chloro-2-fluorophenyl)piperazin-1-yl)ethyl)-3-methyl-1H-indazol-1-yl)piperidine-2,6-dione (CAS CATO-C3D-263207)
- 3-(4-Methylphenyl)-1,2-thiazole-4-carboxylic acid (CAS 67049-13-2)
- cis-3,5-Dimethylpiperidine (CAS 14446-75-4)
- 1-Allyl-4-methylpyridin-1-ium bromide (CAS 10129-54-1)
- 4-(Chloromethyl)-2-[3-(trifluoromethyl)phenyl]-1,3-oxazole (CAS 1005336-35-5)
- 2,3-Dihydrofuro[3,2-b]pyridin-5-amine (CAS 95837-11-9)
- 2-Bromo-3-trimethylsilanyl-isonicotinic acid methyl ester (CAS 848243-28-7)
- Methyl 2-ethyl-2-(methylamino)butanoate (CAS 1183614-61-0)
- 864071-08-9 Perfluorooctanoic Acid-13C2 (CAS 864071-08-9)
- 2-Chloro-1-(3-chloro-2-methylphenyl)ethan-1-one (CAS 60988-74-1)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
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