5-(2-Fluorophenyl)thiophene-2-carboxylic acid CAS 893733-09-0

Purity 97%+In StockPharmaceutical Standards
CAS No.893733-09-0
Molecular FormulaC11H7FO2S
Molecular Weight222.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(2-Fluorophenyl)thiophene-2-carboxylic acid CAS 893733-09-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(2-Fluorophenyl)thiophene-2-carboxylic acid.

5-(2-Fluorophenyl)thiophene-2-carboxylic acid (CAS 893733-09-0) is a high-purity analytical reference standard with the molecular formula C11H7FO2S and a molecular weight of 222.24 g/mol.

Structurally, 5-(2-Fluorophenyl)thiophene-2-carboxylic acid (C11H7FO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 222.24 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(2-Fluorophenyl)thiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H7FO2S
Molecular Weight222.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Sulfur Atoms1

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