2-Fluoro-4-(5-pyrimidinyl)aniline CAS 893737-75-2
| CAS No. | 893737-75-2 |
| Molecular Formula | C10H8FN3 |
| Molecular Weight | 189.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Fluoro-4-(5-pyrimidinyl)aniline (C10H8FN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-Fluoro-4-(5-pyrimidinyl)aniline (CAS 893737-75-2), molecular formula C10H8FN3 and molecular weight 189.19 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Fluoro-4-(5-pyrimidinyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8FN3 |
| Molecular Weight | 189.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 4-fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (CAS 1016241-81-8)
- 7-fluoro-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1159831-08-9)
- 6-fluoro-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1159831-12-5)
- 8-fluoro-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1159831-26-1)
- 6-Fluoro-[2,3'-bipyridin]-6'-amine (CAS 1177269-58-7)
- 5-Fluoro-3-phenylpyridin-2(1H)-one (CAS 1196145-49-9)
- 6-fluoro-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1208493-13-3)
- 5-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1211586-74-1)
Recommended Standards
- 2-Amino-6-hydroxybenzenesulfonic acid (CAS 66621-35-0)
- 2-fluoro-7-isocyanato-tricyclo[6.2.0.0³⁶]deca-1,3(6),7-triene (CAS 2894830-99-8)
- 2-(4-Fluorophenyl)pyridin-3-ol (CAS 478483-55-5)
- 3-(2,4-Dioxothiazolidin-3-yl)propanoic acid (CAS 49629-36-9)
- 2-phenyl-2-(phenylmethoxycarbonylamino)acetic acid 2-phenyl-2-(phenylmethoxycarbonylamino)ethanoic acid 53990-33-3 A829893 (CAS 53990-33-3)
- N-Benzyl-N-methylpiperidin-3-amine (CAS 1110700-77-0)
- (R)-2-phenylpiperidine hcl (CAS 58613-58-4)
- 2,5-Dibenzyloctahydropyrrolo[3,4-c]pyrrole (CAS 165894-00-8)
- ( inverted exclamation markA)-trans-1,3-Diphenylallyl acetate 87751-69-7 Acetic acid trans-1,3-diphenylallyl ester trans-3-Acetoxy-1,3-diphenylpropene (CAS 87751-69-7)
- N-(1-(thiophen-2-yl)ethyl)methanesulfonamide (CAS 1341292-82-7)
- 5-Amino-8-((4-((4,6-dichloro-1,3,5-triazin-2-yl)amino)-3-sulfophenyl)amino)-9,10-dioxo-9,10-dihydroanthracene-1,2-disulfonic acid (CAS 94087-01-1)
- 7h-Purine-8-thiol (CAS 583-40-4)
- N-cyclohexyl-N-methyl-3-oxopiperazine-1-sulfonamide (CAS 1197479-26-7)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
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