5-(4-(trifluoromethyl)phenyl)pyridin-2-amine CAS 893738-30-2
| CAS No. | 893738-30-2 |
| Molecular Formula | C12H9F3N2 |
| Molecular Weight | 238.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-(trifluoromethyl)phenyl)pyridin-2-amine (CAS 893738-30-2) is a high-purity analytical reference standard with the molecular formula C12H9F3N2 and a molecular weight of 238.21 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 5-(4-(trifluoromethyl)phenyl)pyridin-2-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 238.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-(trifluoromethyl)phenyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2 |
| Molecular Weight | 238.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
- 6-(3-(Trifluoromethyl)phenyl)pyridin-2-amine (CAS 1159819-59-6)
- 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1171920-15-2)
- 5-Phenyl-3-(trifluoromethyl)pyridin-2-amine (CAS 1186194-94-4)
- 5-(2-(Trifluoromethyl)phenyl)pyridin-3-amine (CAS 1224740-83-3)
- 5-(4-(Trifluoromethyl)phenyl)pyridin-3-amine (CAS 1225829-49-1)
- 5-(3-(Trifluoromethyl)phenyl)pyridin-3-amine (CAS 1226168-85-9)
- 3-Phenyl-4-(trifluoromethyl)pyridin-2-amine (CAS 1242530-14-8)
- 3-(4-(Trifluoromethyl)phenyl)pyridin-4-amine (CAS 1261494-14-7)
Recommended Standards
- 5-(2-(Trifluoromethyl)phenyl)pyridin-2-amine (CAS 875166-90-8)
- 5-(trifluoromethyl)-1H-indazole-3-carboxylic acid (CAS 959236-67-0)
- 4-(Trifluoromethyl)diphenyl ether (CAS 2367-02-4)
- 6-(trifluoromethyl)-1H-indazole-3-carboxylic acid (CAS 887576-98-9)
- 2,2-Dimethyl-2-methoxybutyrophenone (CAS 898765-04-3)
- 3-Phenyl-1H-pyrazole 3-phenylpyrazole 3-phenylpyrazol 3(5)-phenyl-1h-pyrazole 3-phenyl-pyrazole 2458-26-6 (CAS 2458-26-6)
- 4-(Diethylamino)benzoyl chloride (CAS 65072-47-1)
- 4-((1H-pyrazol-1-yl)methyl)benzonitrile (CAS 179057-34-2)
- Ethyl 6-(chloromethyl)-4-(1-ethyl-1h-pyrazol-4-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 1005627-70-2)
- 4-(chloromethyl)-2-nitrothiophene (CAS 1092561-29-9)
- 3-(Cyclopropylamino)-2-methylpropanoic acid (CAS 1155528-94-1)
- 1-(4-(2-Hydroxyethyl)-2-methylpiperazin-1-yl)ethanone (CAS 1353954-58-1)
- Diisopropyl 1-tosylpiperidine-4,4-dicarboxylate (CAS 1523618-00-9)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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