1-(3-Methoxybenzyl)piperazin-2-one CAS 893747-81-4
| CAS No. | 893747-81-4 |
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Methoxybenzyl)piperazin-2-one.
1-(3-Methoxybenzyl)piperazin-2-one (CAS 893747-81-4) is a high-purity analytical reference standard with the molecular formula C12H16N2O2HCl and a molecular weight of 256.73 g/mol.
1-(3-Methoxybenzyl)piperazin-2-one (C12H16N2O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-Methoxybenzyl)piperazin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O2 HCl |
| Molecular Weight | 256.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methoxybenzyl Standards
- 2-((2-Methoxybenzyl)(methyl)amino)ethanol (CAS 100054-98-6)
- 1-(1-(4-methoxybenzyl)-1H-1,2,3-triazol-4-yl)ethan-1-one (CAS 1001112-90-8)
- 2-((4-Methoxybenzyl)amino)ethanol hydrochloride (CAS 100132-03-4)
- 1-(3-Methoxybenzyl)-3,5-dimethyl-1h-pyrazol-4-amine (CAS 1001519-29-4)
- 1-(4-Methoxybenzyl)-1H-pyrazol-3-amine (CAS 1003011-46-8)
- 3-(4-Methoxybenzyl)pyrrolidine (CAS 1003561-92-9)
- n-(2-Methoxybenzyl)-1-(1-methyl-1h-pyrazol-5-yl)methanamine (CAS 1006438-71-6)
- N-(4-methoxybenzyl)-1-(1-methyl-1H-pyrazol-4-yl)methanamine (CAS 1006476-23-8)
Recommended Standards
- 2-amino-3-(4-(trifluoromethyl)phenyl)propanoic acid hydrochloride (CAS 167496-28-8)
- 4-fluoro-5-((7-fluorobenzo[d][1,3]dioxol-4-yl)methyl)benzo[d][1,3]dioxole (CAS CATO-C3D-263190)
- 5-[(8-Chloro-3-isoquinolinyl)amino]-3-[(1R)-2-(dimethylamino)-1-methylethoxy]-2-pyrazinecarbonitrile (CAS 1184843-57-9)
- 2-(4-Isopropylphenyl)-2-morpholinoacetic acid (CAS 1017321-20-8)
- Brimonidine Impurity 27 (CAS 185312-10-1)
- [(1,5-diethyl-1H-pyrazol-4-yl)methyl]amine (CAS 1007540-87-5)
- 2,3,5,6-Tetrachloroterephthalamide (CAS 1786-85-2)
- 6-O-alpha-D-Mannopyranosyl-D-mannose (CAS 6614-35-3)
- 4-Bromo-3-nitropyridine-2-sulfonyl chloride (CAS 1805558-16-0)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com