3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid CAS 893754-27-3
| CAS No. | 893754-27-3 |
| Molecular Formula | C10H7F3N2O2S |
| Molecular Weight | 276.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid (C10H7F3N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid (CAS 893754-27-3), a certified reference material (molecular formula C10H7F3N2O2S, MW 276.23 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7F3N2O2S |
| Molecular Weight | 276.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-6-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid (CAS 610259-30-8)
- Methyl 3-amino-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate (CAS 866038-91-7)
- Methyl 3-amino-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate (CAS 439095-90-6)
- 4-AMino-5-(2-trifluoromethoxy-phenyl)-4h-[1,2,4]triazole-3-thiol (CAS 1174189-81-1)
- 3-Amino-3-(5-(4-nitrophenyl)furan-2-yl)propanoic acid (CAS 773125-51-2)
- 5-Amino-2-(1,3-dioxoisoindolin-2-yl)-5-oxopentanoic Acid (CAS 7607-72-9)
- 5-Amino-4-(1,3-dioxoisoindolin-2-yl)-5-oxopentanoic acid (CAS 2614-09-7)
- Ethyl 5-amino-1-(2-nitrophenyl)-1H-pyrazole-3-carboxylate (CAS 1264045-48-8)
Recommended Standards
- 3-(3,4-Difluorobenzoyl)phenyl acetate (CAS 890100-20-6)
- 3-(2,6-Difluorobenzoyl)phenyl acetate (CAS 890100-18-2)
- 4-(2,3-Difluorobenzoyl)phenyl acetate (CAS 890099-95-3)
- 3-(2,5-Difluorobenzoyl)phenyl acetate (CAS 890100-16-0)
- (2-Ethoxy-4-methyl-phenoxy)-acetic acid (CAS 878425-43-5)
- 4,7,10,13,16,19,22,25-Octaoxa-28-azahentriacontanoic acid, 31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-, 2,5-dioxo-1-pyrrolidinyl Ester 756525-93-6 (CAS 756525-93-6)
- N-(4-Chlorophenyl)-2-[2-(4-methoxyphenoxy)acetyl]-1-hydrazinecarboxamide (CAS 648915-34-8)
- 1-Benzoyl-4-piperidone (CAS 24686-78-0)
- 6-Amino-1,4-dimethyl-1,4-dihydroquinoxaline-2,3-dione (CAS 76097-86-4)
- 2-(3,4-Dimethoxyphenyl)imidazole (CAS 1119531-20-2)
- 6-(2-(Piperidin-1-yl)ethyl)-9H-purine (CAS 920503-27-1)
- N,4-Dimethyl-N-phenylbenzenesulfonamide (CAS 599-62-2)
- 1-(4,5-Dimethylthiophen-2-yl)-1H-pyrrole-2-carbaldehyde (CAS 62033-75-4)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
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