Fluconazole EP Impurity A CAS 89429-59-4
| CAS No. | 89429-59-4 |
| Molecular Formula | C13H12F2N6O |
| Molecular Weight | 306.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Fluconazole EP Impurity A (CAS 89429-59-4), a pharmacopoeial impurity reference standard (molecular formula C13H12F2N6O, MW 306.27 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fluconazole EP Impurity A (C13H12F2N6O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Fluconazole EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12F2N6O |
| Molecular Weight | 306.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Fluconazole Standards
- Fluconazole EP Impurity A (R-Isomer) (CAS CATO-C4X-101963)
- Fluconazole (CAS 86386-73-4)
- Fluconazole Impurity 37 (CAS CATO-C4X-101937)
- Fluconazole-d4 (CAS 1124197-58-5)
- Fluconazole EP Impurity H (CAS 150194-52-8)
- Fluconazole EP Impurity H (R-Isomer) (CAS CATO-C4X-101966)
- Fluconazole Impurity 48 (CAS 1222655-38-0)
- Fluconazole Impurity 61 (CAS CATO-C4X-101961)
Recommended Standards
- MMG-11 (CAS 313254-94-3)
- methyl 5-methyl-4-[(5-methyl-2-nitrophenoxy)methyl]isoxazole-3-carboxylate (CAS 938006-51-0)
- Lenalidomide Impurity 74 (CAS CATO-C4X-190374)
- FA-Ala-OSu (M-1345.0001) (CAS 76079-01-1)
- Glycyrrhizic Acid Impurity 11 (CAS CATO-C4X-253711)
- Bupivacaine Impurity 17 (CAS CATO-C4X-148217)
- Cefditoren Impurity 66 (CAS CATO-C4X-135866)
- 1-(3-Methylphenyl)-1h-pyrazole-4-sulfonamide (CAS 1249572-37-9)
- 2-bromoethyl sulfonate ethyl ester (CAS CATO-C4X-169214)
- 2'-Anilino-6'-(dibutylamino)-3'-methylfluoran (CAS 89331-94-2)
- 1-(2-Chlorobenzyl)piperidin-4-amine (CAS 92539-15-6)
- Mephentermine Impurity 1 (CAS 26187-18-8)
- tert-Butyl ((2-oxoimidazolidin-4-yl)methyl)carbamate (CAS 2288676-96-8)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com