5-fluoro-1,2-benzoxazole-3-carboxylic acid CAS 894789-50-5
| CAS No. | 894789-50-5 |
| Molecular Formula | C8H4FNO3 |
| Molecular Weight | 181.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-fluoro-1,2-benzoxazole-3-carboxylic acid.
5-fluoro-1,2-benzoxazole-3-carboxylic acid (CAS 894789-50-5), molecular formula C8H4FNO3 and molecular weight 181.12 g/mol, is a CATO reference standard with documented purity and traceability.
5-fluoro-1,2-benzoxazole-3-carboxylic acid (C8H4FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4FNO3 |
| Molecular Weight | 181.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-Fluorobenzo[d]oxazole-2-carboxylic acid (CAS 944907-34-0)
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- 5-Fluoro-4-nitro-1H-benzo[d]imidazole (CAS 391906-61-9)
- Ethyl 2-(4-bromo-2-methylphenyl)thiazole-4-carboxylate (CAS 886368-25-8)
- Podospicatin (CAS 479-97-0)
- 3-Bromo-5-ethoxy-1-(methoxymethyl)-1H-1,2,4-triazole (CAS 1706431-13-1)
- 6-cyano-1-methyl-indole-3-sulfonyl chloride (CAS 1158209-55-2)
- Etifoxine Hydrochloride (CAS 56776-32-0)
- 5-(4-Aminophenyl)-3-methylpyrazin-2(1H)-one (CAS 89541-81-1)
- trans,trans-Farnesol (CAS 106-28-5)
- 2-(((1-(2-Fluoroethyl)-4-methyl-1H-pyrazol-5-yl)amino)methyl)benzoic acid hydrochloride (CAS 1855939-81-9)
- 2-Chloro-5,7-dimethylbenzoxazole (CAS 1181394-66-0)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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