6-(hydroxymethyl)-5-methylpyrimidine-2,4-diol CAS 89532-98-9
| CAS No. | 89532-98-9 |
| Molecular Formula | C6H8N2O3 |
| Molecular Weight | 156.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(hydroxymethyl)-5-methylpyrimidine-2,4-diol (CAS 89532-98-9) is a high-purity analytical reference standard with the molecular formula C6H8N2O3 and a molecular weight of 156.14 g/mol.
The molecular framework of 6-(hydroxymethyl)-5-methylpyrimidine-2,4-diol (C6H8N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O3 |
| Molecular Weight | 156.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 2 |
Related hydroxymethyl Standards
- Methyl 1-(hydroxymethyl)-1h-pyrazole-3-carboxylate (CAS 1001519-16-9)
- 5-(hydroxymethyl)-3-methylfuran-2-carboxylic acid (CAS 121756-65-8)
- Methyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate (CAS 124598-39-6)
- 2-(4-(Hydroxymethyl)-1H-1,2,3-triazol-1-yl)acetamide (CAS 1250643-76-5)
- 5-(hydroxymethyl)-4-methylfuran-2-carboxylic acid (CAS 130446-62-7)
- 5-(Hydroxymethyl)-2-methylfuran-3-carboxylic acid (CAS 15341-68-1)
- 3,5-Bis(hydroxymethyl)furan-2-carbaldehyde (CAS 191487-05-5)
- 2,6-Bis(hydroxymethyl)pyrimidin-4(1H)-one (CAS 193071-37-3)
Recommended Standards
- 6-(Hydroxymethyl)-1-methylpyrazine-2,3(1H,4H)-dione (CAS 61481-37-6)
- 6-Acetoxy-2H-pyran-3(6H)-one (CAS 62644-49-9)
- 5-Isopropyl-1,2,4-oxadiazole-3-carboxylic acid (CAS 774511-34-1)
- 6A-methyldihydrofuro[2,3-b]furan-2,5(3H,6aH)-dione (CAS 98546-44-2)
- 3-Carbamoyl-4-carboxy-1,2,5-oxadiazole 2-oxide (CAS 204335-82-0)
- (R)-2-((2-Benzamidopropanoyl)thio)acetic acid (CAS 138079-74-0)
- Ethyl 6-bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1431978-00-5)
- 2-(2-(Chlorosulfonyl)-6,7-dihydro-4h-thieno[3,2-c]pyran-4-yl)acetic acid (CAS 1258640-16-2)
- Deca-2,4,6,8-tetraenal (CAS 40650-87-1)
- trans-1-(4-Ethylcyclohexyl)-4-ethynylbenzene (CAS 1369510-20-2)
- 2-[2-(Dimethylamino)phenyl]acetonitrile (CAS 1000512-16-2)
- Ammonium Glycyrrhizate (CAS 53956-04-0)
- Potassium hexacyanoferrate(II)-<SUP>13</SUP>C<SUB>6</SUB> trihydrate (CAS 190394-78-6)
- Akt/SKG Substrate Peptide (CAS 276680-69-4)
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