O-(4-Hydroxy-2,5-dioxotetrahydrofuran-3-yl) butanethioate CAS 89588-04-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including O-(4-Hydroxy-2,5-dioxotetrahydrofuran-3-yl) butanethioate.

O-(4-Hydroxy-2,5-dioxotetrahydrofuran-3-yl) butanethioate (CAS 89588-04-5) is a high-purity analytical reference standard with the molecular formula C8H10O5S and a molecular weight of 218.23 g/mol.

The molecular framework of O-(4-Hydroxy-2,5-dioxotetrahydrofuran-3-yl) butanethioate (C8H10O5S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), O-(4-Hydroxy-2,5-dioxotetrahydrofuran-3-yl) butanethioate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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