6-Chloro-N2-methylpyridine-2,3-diamine CAS 89660-14-0
| CAS No. | 89660-14-0 |
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrile group, chlorine substitution, an aromatic ring system, 6-Chloro-N2-methylpyridine-2,3-diamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 157.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-Chloro-N2-methylpyridine-2,3-diamine (CAS 89660-14-0), molecular formula C6H8ClN3 and molecular weight 157.60 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-N2-methylpyridine-2,3-diamine (CAS 100114-37-2)
- 4-Chloro-3-ethoxypyridine (CAS 1003711-81-6)
- 5-Chloro-2,3-dimethylpyridine 1-oxide (CAS 1015057-46-1)
- 2-Chloro-5-(methoxymethyl)pyridine (CAS 1016534-59-0)
- 3-Chloro-5-methoxyaniline (CAS 10272-06-7)
- 3-Chloro-5-(methylamino)phenol (CAS 1082113-30-1)
- (6-Chloro-2-methylpyridin-3-yl)methanol (CAS 1093879-95-8)
- 2-Chloro-4-methoxy-5-methylpyridine (CAS 1122090-84-9)
Recommended Standards
- 6-Chloro-N,2-dimethylpyrimidin-4-amine (CAS 5621-01-2)
- 6-Chloro-N4-methylpyridine-3,4-diamine (CAS 87034-76-2)
- 6-Chloro-4-ethylpyridazin-3-amine (CAS 933035-42-8)
- N-[(2-Chlorophenyl)methyl]hydroxylamine (CAS 55606-45-6)
- (R)-2-[3-(4-Cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetic acid, 97% (CAS 181023-08-5)
- (1S,2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-((R)-1-hydroxyallyl)cyclopent-3-ene-1,2-diol (CAS 194353-47-4)
- 3,7-dimethyldecane (CAS 17312-54-8)
- N-(3-chlorophenyl)-2,3-dihydro-4H-benzo[b][1,4]thiazine-4-carboxamide (CAS 182128-49-0)
- 1,1-Dibromo-2-(4-methylphenyl)-1-ethene (CAS 60512-56-3)
- N-((3-Methylisoxazol-5-yl)carbamothioyl)benzamide (CAS 118385-15-2)
- Ethyl 2-(hydroxyimino)-2-(1H-imidazol-1-yl)acetate (CAS 95080-92-5)
- 4-(3-Fluorophenoxy)butan-2-amine (CAS 1038717-82-6)
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