5-Chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one CAS 89660-20-8
| CAS No. | 89660-20-8 |
| Molecular Formula | C7H6ClN3O |
| Molecular Weight | 183.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one.
CATO supplies 5-Chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one (CAS 89660-20-8), a certified reference material (molecular formula C7H6ClN3O, MW 183.60 g/mol) for analytical method development and quality control.
Structurally, 5-Chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one (C7H6ClN3O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 183.60 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3O |
| Molecular Weight | 183.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 100367-42-8)
- 4-Chloro-3,6-dimethylisoxazolo[5,4-d]pyrimidine (CAS 1023758-00-0)
- (6-Chloro-7H-purin-8-yl)methanamine (CAS 1044770-59-3)
- 7-Chloro-5-methoxy-1H-benzo[d][1,2,3]triazole (CAS 1086836-89-6)
- 6-Chloro-3-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one (CAS 120422-89-1)
- 2-Chloro-8-methoxy-[1,2,4]triazolo[1,5-a]pyridine (CAS 1207970-17-9)
- 4-Chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one (CAS 1226804-06-3)
- 2-Chloro-4-hydrazinyl-5H-pyrrolo[2,3-d]pyrimidine (CAS 1260667-61-5)
Recommended Standards
- 5-Chloro-2-hydrazinylbenzo[d]oxazole (CAS 64037-22-5)
- 6-Amino-4-chloro-1H-benzo[d]imidazol-2(3H)-one (CAS 59674-84-9)
- 5-Chloro-1-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one (CAS 40852-06-0)
- 6-Amino-4-chloro-1H-indazol-3-ol (CAS 91775-38-1)
- rel-(3R,4S)-3-Cyclopropyl-4-(hydroxymethyl)-1-(4-methoxybenzyl)-2-oxopyrrolidine-3-carbonitrile (CAS 1891013-86-7)
- (S)-3-amino-2-oxopiperidine-1-carboximidamide (CAS 1202553-69-2)
- Tert-butyl 4-((3-methoxybenzyl)amino)piperidine-1-carboxylate (CAS 1233958-38-7)
- Diethyl 2-(((4-benzoyl-5-methyl-1H-pyrrol-3-yl)amino)methylene)malonate (CAS 131169-01-2)
- Furan-2-yl(naphthalen-1-yl)methanol (CAS 873974-71-1)
- tert-Butyl 6,6a,7,7a-tetrahydro-5H-cyclopropa[c][1,5]naphthyridine-5-carboxylate (CAS 2417969-64-1)
- 6,6'-Disulfanediylbis(2-bromoaniline) (CAS 1820605-11-5)
- Isoxicam (CAS 34552-84-6)
- Methyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propanoate (CAS 1018781-64-0)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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