5-(Chloroacetyl)-1,3-dimethyl-1,3-dihydro-2H-benzimidazol-2-one CAS 897545-61-8
| CAS No. | 897545-61-8 |
| Molecular Formula | C11H11ClN2O2 |
| Molecular Weight | 238.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(Chloroacetyl)-1,3-dimethyl-1,3-dihydro-2H-benzimidazol-2-one (C11H11ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 5-(Chloroacetyl)-1,3-dimethyl-1,3-dihydro-2H-benzimidazol-2-one (CAS 897545-61-8), a certified reference material (molecular formula C11H11ClN2O2, MW 238.67 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(Chloroacetyl)-1,3-dimethyl-1,3-dihydro-2H-benzimidazol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClN2O2 |
| Molecular Weight | 238.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroacetyl Standards
- 6-(2-chloroacetyl)-3-methyl-1,2,3,4-tetrahydroquinazolin-2-one (CAS 118621-05-9)
- 1-(Chloroacetyl)-4-phenylpiperidine (CAS 87358-96-1)
- 5-(2-chloroacetyl)-3,3-dimethyl-2,3-dihydro-1H-indol-2-one (CAS 122281-02-1)
- 7-(chloroacetyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one (CAS 154195-54-7)
- 1-[4-(chloroacetyl)phenyl]pyrrolidin-2-one (CAS 923200-17-3)
- 6-(2-chloroacetyl)-1-methyl-1,2,3,4-tetrahydroquinolin-2-one (CAS 221692-28-0)
- N-(4-(2-chloroacetyl)phenyl)cyclopropanecarboxamide (CAS 919724-49-5)
- 6-(2-Chloroacetyl)-4-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 114566-43-7)
Recommended Standards
- 5-(3-Chloro-phenyl)-5-ethyl-imidazolidine-2,4-dione (CAS 250352-06-8)
- 5-(Chloromethyl)-1-(4-ethoxyphenyl)-1H-tetrazole (CAS 552814-58-1)
- 5-(1-chloroethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole (CAS 91066-38-5)
- 5-(Chloromethyl)-3-((p-tolyloxy)methyl)-1,2,4-oxadiazole (CAS 850375-37-0)
- 7-Fluoro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one (CAS 1510826-19-3)
- (Aminomethyl)trimethoxysilane 1-(Trimethoxysilyl)methanamine 71408-48-5 SLM 88705 (CAS 71408-48-5)
- 3-Bromo-N-((2-hydroxy-5-oxopyrrolidin-2-yl)methyl)-2,6-dimethoxybenzamide (CAS 125558-31-8)
- 5-Fluoro-2-(1h-tetraazol-1-yl)aniline (CAS 869942-04-1)
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