6-Chloro-2-(2,5-dimethoxyphenyl)quinoline-4-carboxylic acid CAS 897560-34-8
| CAS No. | 897560-34-8 |
| Molecular Formula | C18H14ClNO4 |
| Molecular Weight | 343.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-2-(2,5-dimethoxyphenyl)quinoline-4-carboxylic acid.
CATO supplies 6-Chloro-2-(2,5-dimethoxyphenyl)quinoline-4-carboxylic acid (CAS 897560-34-8), a certified reference material (molecular formula C18H14ClNO4, MW 343.76 g/mol) for analytical method development and quality control.
The molecular framework of 6-Chloro-2-(2,5-dimethoxyphenyl)quinoline-4-carboxylic acid (C18H14ClNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14ClNO4 |
| Molecular Weight | 343.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-N-(3-(4-methoxyphenyl)-4-oxo-4H-chromen-2-yl)acetamide (CAS 1017420-44-8)
- 3-[(5-chloro-2-fluorophenyl)sulfamoyl]-4-methylbenzoic acid (CAS 1030709-48-8)
- 6-Chloro-2-(3,4-dimethoxyphenyl)quinoline-4-carboxylic acid (CAS 19021-16-0)
- (4-{[(4-chloro-2-fluorophenyl)sulfonyl]amino}phenyl)acetic acid (CAS 794584-38-6)
- 2-(4-Chloro-2-methylphenoxy)-1-((2-hydroxy-1H-indol-3-yl)diazenyl)ethan-1-one (CAS 321966-67-0)
- 2-Chloro-3-[(2,5-dimethoxyphenyl)amino]-1,4-dihydronaphthalene-1,4-dione (CAS 331462-39-6)
- 2-Chloro-5-[(4-fluorophenyl)(methyl)sulfamoyl]benzoic acid (CAS 379254-58-7)
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Recommended Standards
- 4-(3-Chloro-4,5-dimethoxybenzylidene)-2-phenyloxazol-5(4H)-one (CAS 7000-46-6)
- 8-Chloro-2-(2,5-dimethoxyphenyl)quinoline-4-carboxylic acid (CAS 862782-47-6)
- 4-(2-Chloro-3,4-dimethoxybenzylidene)-2-phenyloxazol-5(4H)-one (CAS 6831-50-1)
- 8-Chloro-2-(3,4-dimethoxyphenyl)quinoline-4-carboxylic acid (CAS 862782-46-5)
- 2-(4-Chloro-6-(difluoromethyl)-5-iodopyridin-2-yl)acetonitrile (CAS 1806934-53-1)
- 2-[(trifluoromethyl)sulfanyl]pyridine (CAS 57830-49-6)
- (S)-2-Amino-N-((6-bromopyridin-3-yl)methyl)-N-isopropyl-3-methylbutanamide (CAS 1353996-01-6)
- (S)-5-tert-Butyl 6-methyl 2-iodo-3-((2-(trimethylsilyl)ethoxy)methyl)-6,7-dihydro-3H-imidazo[4,5-c]pyridine-5,6(4H)-dicarboxylate (CAS 2243987-13-3)
- 1-Bromo-3-(difluoromethyl)-2-fluorobenzene (CAS 1204333-52-7)
- 2-(Adamantane-1-carboxamido)butanoic acid (CAS 1009266-16-3)
- 5α-tetrahydrocortisol d5 (CAS 252976-07-1)
- N-(4-Bromo-2-chlorophenyl)benzamide (CAS 902091-22-9)
- 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1H-pyrazole (CAS 2096995-02-5)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
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