2,2'-Bis(trifluoromethyl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid CAS 89803-71-4
| CAS No. | 89803-71-4 |
| Molecular Formula | C16H8F6O4 |
| Molecular Weight | 378.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2,2'-Bis(trifluoromethyl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid (CAS 89803-71-4), a certified reference material (molecular formula C16H8F6O4, MW 378.22 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, 2,2'-Bis(trifluoromethyl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H8F6O4 |
| Molecular Weight | 378.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
Related Bis Standards
- 3,3'-Bis(trifluoromethyl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid (CAS 203007-70-9)
- (3,5-Bis(trifluoromethyl)phenyl)(3,4-dimethoxyphenyl)methanone (CAS 1310355-49-7)
- 1-(3,5-Bis(trifluoromethyl)benzyl)-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338782-03-9)
- 4-((2,4-Bis(trifluoromethyl)benzyl)oxy)-3-methoxybenzaldehyde (CAS 796844-14-9)
- Methyl 2-(2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetoxy)benzoate (CAS 672950-97-9)
- 5-(((Trifluoromethyl)sulfonyl)oxy)-7,8-dihydronaphthalen-2-yl pivalate (CAS 2226904-85-2)
- N-{3-[5-(trifluoromethyl)pyridin-2-yl]phenyl}benzenesulfonamide (CAS 1092346-19-4)
- 4-(4-Methyl-5-(2-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)bicyclo[2.2.2]octane-1-carboxamide (CAS 719274-83-6)
Recommended Standards
- 2-(5-Bromo-4-formyl-2-methoxyphenoxy)-N-(p-tolyl)acetamide (CAS 832674-06-3)
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- 2-(5-bromo-4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide (CAS 486994-13-2)
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- tert-Butyl 7-bromo-4,5-dihydro-3H-spiro[benzo[b][1,4]oxazepine-2,4'-piperidine]-1'-carboxylate (CAS 1956380-84-9)
- (3R,4S)-4-(2-chloro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1784747-76-7)
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