5-Chloro-N-(2-ethoxyphenyl)-2-(methylthio)pyrimidine-4-carboxamide CAS 898646-93-0
| CAS No. | 898646-93-0 |
| Molecular Formula | C14H14ClN3O2S |
| Molecular Weight | 323.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 323.80 g/mol gives 5-Chloro-N-(2-ethoxyphenyl)-2-(methylthio)pyrimidine-4-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-Chloro-N-(2-ethoxyphenyl)-2-(methylthio)pyrimidine-4-carboxamide (CAS 898646-93-0), a certified reference material (molecular formula C14H14ClN3O2S, MW 323.80 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-N-(2-ethoxyphenyl)-2-(methylthio)pyrimidine-4-carboxamide (C14H14ClN3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-N-(2-ethoxyphenyl)-2-(methylthio)pyrimidine-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14ClN3O2S |
| Molecular Weight | 323.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 1216398-85-4 4-[4-(4-Chloro-3-nitrophenyl)-1,3-thiazol-2-yl]piperidine (CAS 1216398-85-4)
- 3-{4-chloro-5-phenylthieno[2,3-d]pyrimidin-2-yl}pyridine (CAS 743453-38-5)
- 3-{4-chloro-6-phenylthieno[2,3-d]pyrimidin-2-yl}pyridine (CAS 885461-04-1)
- 4-(3-Chloro-1-benzothiophen-2-yl)-2,6-dimethylpyridine-3,5-dicarbonitrile (CAS 477886-64-9)
- 4-chloro-6-phenyl-2-pyridin-2-ylthieno[2,3-d]pyrimidine (CAS 885460-37-7)
- 4-Chloro-N-(3-(hydrazinecarbonyl)-4,5-dimethylthiophen-2-yl)benzamide (CAS 299962-36-0)
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Recommended Standards
- 5,6-Dibromo-4-methylthieno[2,3-d][1,2,3]diazaborinin-1(2H)-ol (CAS 58157-84-9)
- N-Allyl-2-((1-(5-chloro-2-methylphenyl)-1H-tetrazol-5-yl)thio)acetamide (CAS 878702-55-7)
- WY-14643 (CAS 50892-23-4)
- Dabsyl Chloride (CAS 56512-49-3)
- 2-(4-(Trifluoromethyl)cyclohexyl)propanoic acid (CAS 1513213-56-3)
- Tert-butyl 4-pivalamidopiperidine-1-carboxylate (CAS 1233955-60-6)
- 6-Amino-5-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridine-3-boronic Acid Pinacol Ester (CAS 877399-08-1)
- 4-(tert-Butyl)-2-(pyrrolidin-2-yl)-1H-imidazole (CAS 1153104-89-2)
- 2-Acetamidoisophthalic acid (CAS 67081-70-3)
- 4-(4-Azidophenyl)butyric acid (CAS 103489-33-4)
- 3-Bromo-6-fluoro-4-nitro-2H-indazole (CAS 885522-77-0)
- N,N-Bis(2-chloroethyl)-4-isocyanatoaniline (CAS 82484-59-1)
- 4-(2,3-Dichlorophenyl)butan-2-ol (CAS 1341106-15-7)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
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