4-Bromo-3-(3-chloro-5-fluorophenyl)-2-fluoropropiophenone CAS 898751-08-1
| CAS No. | 898751-08-1 |
| Molecular Formula | C15H10BrClF2O |
| Molecular Weight | 359.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-3-(3-chloro-5-fluorophenyl)-2-fluoropropiophenone (CAS 898751-08-1), molecular formula C15H10BrClF2O and molecular weight 359.59 g/mol, is a CATO reference standard with documented purity and traceability.
4-Bromo-3-(3-chloro-5-fluorophenyl)-2-fluoropropiophenone (C15H10BrClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10BrClF2O |
| Molecular Weight | 359.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl/Br-containing |
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