3-(3-Chloro-5-fluorophenyl)-1-(3,5-difluorophenyl)propan-1-one CAS 898751-52-5
| CAS No. | 898751-52-5 |
| Molecular Formula | C15H10ClF3O |
| Molecular Weight | 298.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(3-Chloro-5-fluorophenyl)-1-(3,5-difluorophenyl)propan-1-one (CAS 898751-52-5), molecular formula C15H10ClF3O and molecular weight 298.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(3-Chloro-5-fluorophenyl)-1-(3,5-difluorophenyl)propan-1-one (C15H10ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(3-Chloro-5-fluorophenyl)-1-(3,5-difluorophenyl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10ClF3O |
| Molecular Weight | 298.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-2-cyclopropyl-6-(2-(trifluoromethyl)phenyl)pyrimidine (CAS 1159819-79-0)
- 1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-indoline (CAS 1220027-90-6)
- 1-Chloro-2-(trifluoromethyl)-4-(4-vinylphenoxy)benzene (CAS 1369254-73-8)
- (5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl pentanoate (CAS 303148-53-0)
- 3-(3-Chloro-5-fluorophenyl)-1-(2,4-difluorophenyl)propan-1-one (CAS 898751-44-5)
- 3-(3-Chloro-5-fluorophenyl)-1-(3,4-difluorophenyl)propan-1-one (CAS 898751-48-9)
- 4'-Chloro-3-methyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-carbaldehyde (CAS 2624417-81-6)
- N-{2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]vinyl}aniline (CAS 246022-07-1)
Recommended Standards
- 3-(3-Chlorophenyl)-3,4,5-trifluoropropiophenone (CAS 898787-48-9)
- 3-(4-Chlorophenyl)-1-(3,4,5-trifluorophenyl)propan-1-one (CAS 898788-51-7)
- 1-(4-Chlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898777-92-9)
- 1-(3-Chlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898777-90-7)
- 2-Methyl-1,3-dioxolane (CAS 497-26-7)
- n-(5-Bromopyridin-2-yl)-2-(methylamino)acetamide hydrochloride (CAS 1240528-42-0)
- 4-Methylnaphthalene-1-sulfonyl chloride (CAS 10447-11-7)
- 3-chloro-4,5-difluorophenol (CAS 1261472-63-2)
- 4-Methyl-1,3-thiazole-5-carbonitrile (CAS 408526-37-4)
- 1,8-Bis[(4S)-4,5-dihydro-4-methyl-2-oxazolyl]-3,6-diphenyl-9H-carbazole (CAS 757959-64-1)
- Cuprate(4-), [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]-, (SP-4-1)- (CAS 64424-13-1)
- Ethyl 2-(1-oxophthalazin-2(1H)-yl)acetate (CAS 18584-72-0)
- 5-Amino-2-(hydroxymethyl)benzonitrile (CAS 1824662-72-7)
- Exenatide (CAS 141758-74-9（free base）)
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