(2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-fluorophenyl)methanone CAS 898756-05-3
| CAS No. | 898756-05-3 |
| Molecular Formula | C21H22FNO3 |
| Molecular Weight | 355.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 355.40 g/mol gives (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-fluorophenyl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-fluorophenyl)methanone (CAS 898756-05-3), a certified reference material (molecular formula C21H22FNO3, MW 355.40 g/mol) for analytical method development and quality control.
The molecular framework of (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-fluorophenyl)methanone (C21H22FNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-fluorophenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H22FNO3 |
| Molecular Weight | 355.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dioxa Standards
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-fluorophenyl)methanone (CAS 898756-24-6)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-fluorophenyl)methanone (CAS 898756-04-2)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-fluorophenyl)methanone (CAS 898762-01-1)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-fluorophenyl)methanone (CAS 898761-77-8)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-fluorophenyl)methanone (CAS 898761-79-0)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-fluorophenyl)methanone (CAS 898758-08-2)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-fluorophenyl)methanone (CAS 898757-84-1)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-fluorophenyl)methanone (CAS 898757-86-3)
Recommended Standards
- 1-(4-(Diisopropylamino)but-2-yn-1-yl)-3-(2-(trifluoromethyl)phenyl)urea (CAS 1396564-14-9)
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- 1-(5-(4-Fluorophenyl)-5-hydroxypentanoyl)-5-phenylpyrrolidin-2-one (CAS 1027552-46-0)
- Boc-His(Boc)-OH toluene solvate (CAS 20866-46-0)
- 1-(4-Chlorophenyl)-3-(1-(thiophene-2-carbonyl)-1H-pyrazol-3-yl)pyridazin-4(1H)-one (CAS 318498-06-5)
- 3-((4-Chloro-3,5-dimethylphenoxy)methyl)-5-(chloromethyl)-1,2,4-oxadiazole (CAS 263016-09-7)
- Methyl 2-[(3-nitropyridin-2-yl)amino]propanoate (CAS 146294-95-3)
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- tert-butyl N-(1-methyl-3-oxocyclobutyl)carbamate (CAS 1523617-99-3)
- 2-(4-Chlorophenyl)-3-(trifluoromethyl)benzofuran-5-carbonitrile (CAS 821770-06-3)
- 7-Nitro-1,2,3,4-tetrahydro-1,5-naphthyridine (CAS 1393584-97-8)
- 4-(Thiophen-3-yl)-1,8-dioxa-4,11-diazaspiro[5.6]dodecan-3-one (CAS 1422133-94-5)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
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