2,3-Dichloro-3-(3-fluorophenyl)propiophenone CAS 898767-57-2
| CAS No. | 898767-57-2 |
| Molecular Formula | C15H11Cl2FO |
| Molecular Weight | 297.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,3-Dichloro-3-(3-fluorophenyl)propiophenone (C15H11Cl2FO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2,3-Dichloro-3-(3-fluorophenyl)propiophenone (CAS 898767-57-2) is a high-purity analytical reference standard with the molecular formula C15H11Cl2FO and a molecular weight of 297.15 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11Cl2FO |
| Molecular Weight | 297.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- 2,4-Dichloro-7-(4-fluorophenyl)-7-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1356010-00-8)
- 2,3-Dichloro-3-(4-fluorophenyl)propiophenone (CAS 898768-68-8)
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Recommended Standards
- 2-(4-Bromophenyl)-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 885949-90-6)
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- 1-Boc-3-bromo-7-azaindole (CAS 226085-17-2)
- 1-(4-Chloro-2-fluorophenyl)-3-(4-chlorophenyl)propan-1-one (CAS 898788-37-9)
- Difenoxuron (CAS 14214-32-5)
- N-(6-(tert-Butyl)-4-cyclopropoxypyridin-3-yl)methanesulfonamide (CAS 1243283-38-6)
- N~1~,N~1~-dimethyl-1-(3-methyl-2-thienyl)-1,2-ethanediamine hydrochloride (CAS 1185293-39-3)
- tert-butyl 6-amino-5-fluoro-1,2,3,4-tetrahydroisoquinoline-2-carboxylate (CAS 912846-57-2)
- 4-Bromo-N-((1-ethylpyrrolidin-2-yl)methyl)benzamide (CAS 313231-68-4)
- 2-(4-Methylthiazol-5-yl)ethyl octanoate (CAS 163266-17-9)
- 1-Cyclopenten-1-ylbenzene (CAS 825-54-7)
- 2-((4-Ethyl-5-(1-methyl-3-(trifluoromethyl)-1h-pyrazol-5-yl)-4h-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1005700-45-7)
- 4-(4-Chlorophenoxy)benzene-1-sulfonyl chloride (CAS 191327-30-7)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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