1-(3,4-Difluorophenyl)-3-(2-methoxyphenyl)propan-1-one CAS 898774-13-5

Purity 97%+In StockPharmaceutical Standards
CAS No.898774-13-5
Molecular FormulaC16H14F2O2
Molecular Weight276.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(3,4-Difluorophenyl)-3-(2-methoxyphenyl)propan-1-one CAS 898774-13-5 chemical structure

Description

1-(3,4-Difluorophenyl)-3-(2-methoxyphenyl)propan-1-one (CAS 898774-13-5) is a high-purity analytical reference standard with the molecular formula C16H14F2O2 and a molecular weight of 276.28 g/mol.

The molecular framework of 1-(3,4-Difluorophenyl)-3-(2-methoxyphenyl)propan-1-one (C16H14F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(3,4-Difluorophenyl)-3-(2-methoxyphenyl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H14F2O2
Molecular Weight276.28 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing

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