3-Chloro-5-fluoro-3-(4-methoxyphenyl)propiophenone CAS 898776-16-4
| CAS No. | 898776-16-4 |
| Molecular Formula | C16H14ClFO2 |
| Molecular Weight | 292.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Chloro-5-fluoro-3-(4-methoxyphenyl)propiophenone (CAS 898776-16-4), molecular formula C16H14ClFO2 and molecular weight 292.73 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Chloro-5-fluoro-3-(4-methoxyphenyl)propiophenone (C16H14ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 292.73 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 3-Chloro-5-fluoro-3-(4-methoxyphenyl)propiophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClFO2 |
| Molecular Weight | 292.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-2-(2-ethyl-1-piperidinyl)-5-(trifluoromethyl)pyridine (CAS 1219961-17-7)
- 3-Chloro-N-cyclohexyl-N-methyl-5-(trifluoromethyl)-2-pyridinamine (CAS 1220033-24-8)
- 1-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-2-methylpiperazine (CAS 1240573-35-6)
- 1-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-1,4-diazepane (CAS 1240581-71-8)
- 2-((2-Chloro-6-fluorobenzyl)oxy)-3,4-dimethylbenzaldehyde (CAS 1427020-26-5)
- 2-((2-Chloro-4-fluorobenzyl)oxy)-3,4-dimethylbenzaldehyde (CAS 1427028-33-8)
- 1-(2-Chloro-4-fluorophenyl)-3-(3-methoxyphenyl)propan-1-one (CAS 898775-04-7)
- 1-(2-Chloro-4-fluorophenyl)-3-(4-methoxyphenyl)propan-1-one (CAS 898776-13-1)
Recommended Standards
- 3-Chloro-5-fluoro-3-(3-methoxyphenyl)propiophenone (CAS 898775-07-0)
- 4-Chloro-2-fluoro-3-(3-methoxyphenyl)propiophenone (CAS 898775-10-5)
- 3-(3-Chloro-5-fluorophenyl)-4-methoxypropiophenone (CAS 898750-19-1)
- 898774-88-4 1-(4-Chloro-3-fluorophenyl)-3-(3-methoxyphenyl)propan-1-one DTXSID90644235 (CAS 898774-88-4)
- tert-Butyl 8-oxo-6-azaspiro[3.4]octane-6-carboxylate (CAS 1823493-77-1)
- 8-methoxy-3,4-dihydroisoquinoline (CAS 24693-44-5)
- 2-Methyl-2-((4-methylpiperidin-1-yl)sulfonyl)propanehydrazide (CAS 1263214-88-5)
- 3-[(4-Fluorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338405-86-0)
- 2-Chloro-3-fluoro-6-hydroxybenzaldehyde (CAS 1263378-00-2)
- tert-Butyl N-(5-oxooxolan-2-yl)carbamate (CAS 1956382-26-5)
- 4-Bromo-2-formylphenyl 2-chlorobenzoate (CAS 431930-34-6)
- 2-Methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-ol (CAS 1256360-30-1)
- Ethyl 1-[cyano-(4-methoxyphenyl)-methyl]piperidine-4-carboxylate (CAS 1440535-26-1)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com