1-(3-Chloro-5-fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one CAS 898778-45-5

Purity 97%+In StockPharmaceutical Standards
CAS No.898778-45-5
Molecular FormulaC15H9ClF4O
Molecular Weight316.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(3-Chloro-5-fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one CAS 898778-45-5 chemical structure

Description

1-(3-Chloro-5-fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898778-45-5) is a high-purity analytical reference standard with the molecular formula C15H9ClF4O and a molecular weight of 316.68 g/mol.

1-(3-Chloro-5-fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (C15H9ClF4O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(3-Chloro-5-fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H9ClF4O
Molecular Weight316.68 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing

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