(5-(1,3-Dioxolan-2-yl)thiophen-2-yl)(3,4-difluorophenyl)methanone CAS 898778-82-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-(1,3-Dioxolan-2-yl)thiophen-2-yl)(3,4-difluorophenyl)methanone.

(5-(1,3-Dioxolan-2-yl)thiophen-2-yl)(3,4-difluorophenyl)methanone (CAS 898778-82-0), molecular formula C14H10F2O3S and molecular weight 296.29 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, (5-(1,3-Dioxolan-2-yl)thiophen-2-yl)(3,4-difluorophenyl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 296.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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