Ibuprofen Impurity 59 CAS 89878-72-8
| CAS No. | 89878-72-8 |
| Molecular Formula | C18H27ClO2 |
| Molecular Weight | 310.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Ibuprofen Impurity 59 (CAS 89878-72-8), a pharmacopoeial impurity reference standard (molecular formula C18H27ClO2, MW 310.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, a hydroxyl group, an ether linkage, chlorine substitution, Ibuprofen Impurity 59 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 310.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Ibuprofen Impurity 59 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H27ClO2 |
| Molecular Weight | 310.86 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
Related Ibuprofen Standards
- Ibuprofen Impurity 106 (CAS CATO-C4X-1082106)
- Ibuprofen Impurity 107 (CAS CATO-C4X-1082107)
- Ibuprofen Impurity 108 (CAS CATO-C4X-1082108)
- Ibuprofen Impurity 112 (CAS CATO-C4X-1082112)
- Ibuprofen Impurity 60 (CAS 89878-75-1)
- Ibuprofen Impurity 93 (CAS CATO-C4X-108293)
- Ibuprofen Impurity 94 (CAS CATO-C4X-108294)
- Ibuprofen Impurity 95 (CAS 89878-74-0)
Recommended Standards
- Diiodoacetamide (CAS 5875-23-0)
- Ibuprofen Impurity 99 (CAS CATO-C4X-108299)
- 7-(3-(Chlorodimethylsilyl)propoxy)-4-methyl-2H-chromen-2-one (CAS 129119-77-3)
- Trazodone EP Impurity G (CAS 2470436-00-9)
- Gadobutrol Impurity 52 (CAS CATO-C4X-2120152)
- Tetracaine Impurity 42 (CAS CATO-C4X-192342)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
- 3-(4-Ethylphenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 886967-73-3)
- 3-bromothieno[2,3-c]pyridin-7-amine (CAS 1326715-27-8)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-chloro-3-methylbenzoic acid (CAS 2243507-71-1)
- 2-Chloro-4-undecanoylpyridine (CAS 898784-78-6)
- 4-Chloro-N'-(1-(phenylsulfonyl)piperidin-4-ylidene)benzohydrazide (CAS 478248-20-3)
- 4-Chlorophenyl-2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside (CAS 5041-92-9)
- Acetyl Tetrapeptide- 15 (CAS 928007-64-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com