1-(3-Chloro-5-fluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one CAS 898780-94-4
| CAS No. | 898780-94-4 |
| Molecular Formula | C17H16ClFO |
| Molecular Weight | 290.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Chloro-5-fluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one (CAS 898780-94-4), molecular formula C17H16ClFO and molecular weight 290.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-Chloro-5-fluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one (C17H16ClFO) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16ClFO |
| Molecular Weight | 290.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-(2-Chloro-4-fluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one (CAS 898793-16-3)
- 1-(2-Chloro-4-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one (CAS 898794-38-2)
- 1-(2-Chloro-4-fluorophenyl)-3-(2,6-dimethylphenyl)propan-1-one (CAS 898755-12-9)
- 1-(3-Chloro-4-fluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one (CAS 898792-95-5)
- 1-(3-Chloro-4-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one (CAS 898794-24-6)
- 1-(3-Chloro-4-fluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one (CAS 898780-78-4)
- 1-(3-Chloro-5-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one (CAS 898794-40-6)
- 1-(3-Chloro-5-fluorophenyl)-3-(2,5-dimethylphenyl)propan-1-one (CAS 898753-92-9)
Recommended Standards
- 1-(3-Chloro-5-fluorophenyl)-3-(3,4-dimethylphenyl)propan-1-one (CAS 898779-71-0)
- 1-(4-Chloro-2-fluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one (CAS 898793-21-0)
- 1-(3-Chloro-5-fluorophenyl)-3-(2,6-dimethylphenyl)propan-1-one (CAS 898755-14-1)
- 1-(4-Chloro-2-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one (CAS 898794-42-8)
- 2-(5-Methyl-6-(methylamino)pyridin-3-yl)pyrrolidine-1-carbaldehyde (CAS 1352492-71-7)
- 2-(2-Cyanophenyl)-2-methylpropanoic acid (CAS 1314655-77-0)
- benzhydryl (6R,7R)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-7-(4-methylbenzamido)-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (CAS CATO-C4X-179853)
- Methyl propanethioate (CAS 26476-56-2)
- (2E)-1-(4-Ethoxyphenyl)-3-(4-fluorophenyl)prop-2-en-1-one (CAS 1582302-81-5)
- Ethyl nicotinoylglycinate (CAS 54466-74-9)
- (2S)-2-(azidomethyl)oxetane (CAS 2230200-73-2)
- 2-Bromo-1-(4-fluoropyridin-2-yl)ethanone (CAS 1206723-42-3)
- 2-(2-(4-Bromophenyl)-2-oxoethoxy)benzamide (CAS 337925-74-3)
- C-telopeptide (CAS 162929-64-8)
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