5α-ANDROSTAN-17β-OL-3, 6-DIONE CAS 899-39-8
| CAS No. | 899-39-8 |
| Molecular Formula | C19H28O3 |
| Molecular Weight | 304.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5α-ANDROSTAN-17β-OL-3, 6-DIONE is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5α-ANDROSTAN-17β-OL-3, 6-DIONE (CAS 899-39-8), molecular formula C19H28O3 and molecular weight 304.42 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5α-ANDROSTAN-17β-OL-3, 6-DIONE (C19H28O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H28O3 |
| Molecular Weight | 304.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related ANDROSTAN Standards
- 5α-ANDROSTAN-17β-OL-3, 7-DIONE (CAS 55541-91-8)
- 5α-ANDROSTAN-3β-OL-11, 17-DIONE (CAS 7090-90-6)
- 5α-ANDROSTAN-3β-OL-7, 17-DIONE (CAS 49643-99-4)
- 5β-ANDROSTAN-3, 11, 17-TRIONE (CAS 1429-06-7)
- 5α-ANDROSTAN-3, 6, 17-TRIONE (CAS 2243-05-2)
- 5β-ANDROSTAN-3α, 17β-DIOL-11-ONE (CAS 1158-94-7)
- 5β-ANDROSTAN-3α, 16α-DIOL-17-ONE (CAS 14167-50-1)
- 5α-ANDROSTAN-11α, 17β-DIOL-3-ONE (CAS 25788-56-1)
Recommended Standards
- 5-ANDROSTEN-3β, 19-DIOL-17-ONE (CAS 2857-45-6)
- 5-(5,5-Dimethyl-1,3-dioxan-2-yl)-4-ethylvalerophenone (CAS 898755-39-0)
- 4-Hydroxy-17α-methyl-19-nortestosterone (CAS 2747-16-2)
- 4-Ethoxyphenyl trans-4-butylcyclohexanoate (CAS 67589-47-3)
- 2-(2,4-Difluorophenoxy)pyridin-4-amine (CAS 1250599-43-9)
- 2-((Trifluoromethyl)thio)isonicotinonitrile (CAS 1204235-06-2)
- Dimethyl 2-amino-5-iodoterephthalate (CAS 1357367-02-2)
- sodium 5-methyl-2-(4H-1,2,4-triazol-4-yl)benzoate (CAS 1796952-73-2)
- 3'-Carboxy-4'-hydroxyacetoacetanilide (CAS 13243-99-7)
- tert-Butyl (4-(2-chloroacetamido)cyclohexyl)(cyclopropyl)carbamate (CAS 1353980-74-1)
- N-(3-Amino-4-chlorophenyl)-2-(4-chloro-2-methylphenoxy)acetamide (CAS 1020058-46-1)
- 3-(4-Bromo-2-methylphenoxy)-N,N-dimethylpropan-1-amine (CAS 1772995-74-0)
- 1-(2-Fluorophenyl)-3-(propan-2-yl)-4,5-dihydro-1H-pyrazol-5-one (CAS 1092295-70-9)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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