3,5-Difluoro-2-iodophenol CAS 899427-54-4
| CAS No. | 899427-54-4 |
| Molecular Formula | C6H3F2IO |
| Molecular Weight | 255.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3,5-Difluoro-2-iodophenol (CAS 899427-54-4), a certified reference material (molecular formula C6H3F2IO, MW 255.99 g/mol) for analytical method development and quality control.
The molecular framework of 3,5-Difluoro-2-iodophenol (C6H3F2IO) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3F2IO |
| Molecular Weight | 255.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/I-containing |
Related Difluoro Standards
- 3,5-Difluoro-4-iodophenol (CAS 1000574-74-2)
- 3,5-Difluoro-4-iodopyridin-2-amine (CAS 1325215-07-3)
- 2,3-Difluoro-4-iodophenol (CAS 144292-40-0)
- 4,5-Difluoro-2-iodophenol (CAS 186590-30-7)
- 4,6-Difluoro-2-iodopyridin-3-amine (CAS 1934432-95-7)
- 2,4-Difluoro-5-iodophenol (CAS 1935521-44-0)
- 2,4-Difluoro-6-iodophenol (CAS 551002-42-7)
- 2,6-Difluoro-3-iodophenol (CAS 2091451-98-6)
Recommended Standards
- 2,6-Difluoro-4-iodophenol (CAS 950858-06-7)
- 3,6-Difluoro-2-iodophenol (CAS 2092374-07-5)
- 2,6-Difluoro-3-iodopyridin-4-amine (CAS 2756329-77-6)
- 5,7-Dichloro-2-(trifluoromethyl)imidazo[1,2-c]pyrimidine (CAS 1059191-46-6)
- 3-(Cyclopropylsulfamoyl)-4-fluorophenylboronic acid (CAS 1704121-61-8)
- 3-Amino-4-(4-bromophenyl)-1-methylazetidin-2-one (CAS 1291490-66-8)
- 1820748-59-1 Ethyl (2Z)-2-(3-bromo-2-fluorophenyl)-2-hydrazinylideneacetate (CAS 1820748-59-1)
- 1171538-77-4 2-[1-(4-Methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]-6-methylquinoline-4-carboxylic acid MFCD14281710 (CAS 1171538-77-4)
- Methyl 5-cyano-6-(4-fluorophenoxy)-2-methylnicotinate (CAS 303146-31-8)
- Ethyl 2-(3-{[3-(trifluoromethyl)anilino]carbonyl}-2-pyridinyl)acetate (CAS 338392-12-4)
- 6-Bromo-N-(prop-2-yn-1-yl)-3,4-dihydro-2h-1-benzopyran-4-amine (CAS 1158063-61-6)
- 3-(3-(4-(2-Methoxyethoxy)phenyl)isoxazol-5-yl)benzoic acid (CAS 745055-49-6)
- 4-(3-(Aminomethyl)phenyl)thiomorpholine 1,1-dioxide dihydrochloride (CAS 2251053-21-9)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
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