2-Amino-4-(3-methoxyphenyl)thiophene-3-carboxylic acid CAS 899688-10-9
| CAS No. | 899688-10-9 |
| Molecular Formula | C12H11NO3S |
| Molecular Weight | 249.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Amino-4-(3-methoxyphenyl)thiophene-3-carboxylic acid (CAS 899688-10-9), molecular formula C12H11NO3S and molecular weight 249.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Amino-4-(3-methoxyphenyl)thiophene-3-carboxylic acid (C12H11NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 2-Amino-4-(3-methoxyphenyl)thiophene-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11NO3S |
| Molecular Weight | 249.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 5-Amino-2-methoxy-n-(1,3-thiazol-2-yl)benzamide (CAS 1071324-80-5)
- Ethyl 3-amino-5-formylbenzo[b]thiophene-2-carboxylate (CAS 1098608-18-4)
- Ethyl 2-amino-4-(pyridin-2-yl)thiazole-5-carboxylate (CAS 1188153-02-7)
- Methyl 4-amino-2-(phenylamino)thiazole-5-carboxylate (CAS 13807-17-5)
- 6-Amino-1-(4-methoxyphenyl)-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one (CAS 180028-93-7)
- 6-amino-1-(2-methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 180028-94-8)
- Methyl 2-amino-6-phenyl-6H-1,3,4-thiadiazine-5-carboxylate (CAS 185542-74-9)
- 2-Amino-4-(4-methoxyphenyl)thiophene-3-carboxylic acid (CAS 893645-06-2)
Recommended Standards
- 2-{[4-(4-methylphenyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 66297-64-1)
- 2-{[(5-phenyl-1,2-oxazol-3-yl)methyl]sulfanyl}acetic acid (CAS 923212-56-0)
- 2-Ethoxy-N-(1,3,4-thiadiazol-2-yl)benzamide (CAS 349443-13-6)
- 2-{[(5-methylisoxazol-3-yl)methyl]thio}benzoic acid (CAS 854357-41-8)
- (E)-3-(4-fluoro-3-methylphenyl)-4-methylpent-2-enoic acid (CAS 1017354-81-2)
- 6-Bromo-5-(difluoromethyl)-4-nitropicolinaldehyde (CAS 1806858-09-2)
- 8-Chloro-3-iodo-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 2648782-65-2)
- 5,6-Dihydro-4H-cyclopenta[c]thiophene-5-carboxylic acid (CAS 160502-05-6)
- 7-(Trifluoromethyl)-1H-indazole-5-carboxylic acid (CAS 1374258-45-3)
- 2-Chloro-4-(2-fluorophenyl)-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 1707727-98-7)
- 2-Chloro-5-(1,1-dioxidoisothiazolidin-2-yl)benzoic acid (CAS 1183348-44-8)
- 3-Nitro-1-((perfluorophenyl)methyl)-1h-pyrazole (CAS 1006460-78-1)
- N-(3-Mercapto-5-pentyl-4H-1,2,4-triazol-4-yl)benzamide (CAS 32444-84-1)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
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