2-Amino-4-(3-chlorophenyl)thiophene-3-carboxylic acid CAS 899691-53-3

Purity 97%+In StockPharmaceutical Standards
CAS No.899691-53-3
Molecular FormulaC11H8ClNO2S
Molecular Weight253.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-4-(3-chlorophenyl)thiophene-3-carboxylic acid CAS 899691-53-3 chemical structure

Description

The occurrence of 2-Amino-4-(3-chlorophenyl)thiophene-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Amino-4-(3-chlorophenyl)thiophene-3-carboxylic acid (CAS 899691-53-3), molecular formula C11H8ClNO2S and molecular weight 253.70 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Amino-4-(3-chlorophenyl)thiophene-3-carboxylic acid (C11H8ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2-Amino-4-(3-chlorophenyl)thiophene-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8ClNO2S
Molecular Weight253.70 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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