5-Amino-1-(2-chlorobenzyl)-N-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide CAS 899736-99-3
| CAS No. | 899736-99-3 |
| Molecular Formula | C17H16ClN5O |
| Molecular Weight | 341.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Amino-1-(2-chlorobenzyl)-N-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Amino-1-(2-chlorobenzyl)-N-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899736-99-3), a certified reference material (molecular formula C17H16ClN5O, MW 341.79 g/mol) for analytical method development and quality control.
The molecular framework of 5-Amino-1-(2-chlorobenzyl)-N-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide (C17H16ClN5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Amino-1-(2-chlorobenzyl)-N-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H16ClN5O |
| Molecular Weight | 341.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Amino Standards
- 5-Amino-1-(2-chlorobenzyl)-N-(m-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899981-44-3)
- 5-Amino-1-(4-chlorobenzyl)-N-(m-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 900013-54-9)
- 5-Amino-1-(4-chlorophenyl)-N-(1-phenylethyl)-1H-1,2,3-triazole-4-carboxamide (CAS 929832-66-6)
- 5-Amino-1-(4-chlorophenyl)-N-phenethyl-1H-1,2,3-triazole-4-carboxamide (CAS 929864-12-0)
- 5-Amino-1-benzyl-N-(4-chlorobenzyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899749-92-9)
- 5-Amino-4-(benzo[d]thiazol-2-yl)-1-(4-chlorophenyl)-1,3-dihydro-2h-pyrrol-2-one (CAS 885458-21-9)
- 5-Amino-4-benzothiazol-2-yl-1-(4-chloro-phenyl)-1,2-dihydro-pyrrol-3-one (CAS 457638-88-9)
- 6-(5-Amino-3-methyl-1H-pyrazol-1-yl)-1-(4-chlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1172872-30-8)
Recommended Standards
- 5-[1-(4-Chlorophenoxy)ethyl]-N-phenyl-1H-pyrazole-1-carboxamide (CAS 321999-01-3)
- 5-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-2-thiophenesulfonyl chloride (CAS 332361-07-6)
- 5-(3-Chlorophenoxy)-1,3-dimethyl-N-phenyl-1H-pyrazole-4-carboxamide (CAS 303997-92-4)
- 5-(2-Chlorophenyl)-N-(4-methoxybenzyl)furan-2-carboxamide (CAS 853330-28-6)
- 2-Methyl-6-oxo-5-(trifluoromethyl)-1,6-dihydropyridine-3-carbonitrile (CAS 2417423-22-2)
- 6-(Tetrahydro-2H-pyran-4-yloxy)pyridine-2-carboxylic acid (CAS 906352-78-1)
- (3S,4S)-tert-Butyl 3-allyl-4-hydroxypyrrolidine-1-carboxylate (CAS 2165370-65-8)
- N-(tert-butyl)-2-(piperazin-1-yl)-6-(p-tolyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine (CAS 1171889-08-9)
- 15H-Cyclopenta[a]phenanthren-17(16H)-one (CAS 786-66-3)
- Ethyl 3-methoxy-5-(trifluoromethyl)picolinate (CAS 1806497-21-1)
- 1-(5-(tert-Butyl)isoxazol-3-yl)-3-(4-methoxyphenyl)urea (CAS 852670-26-9)
- n-(1-(3-Fluoro-4-methoxyphenyl)ethyl)-3-methylbut-2-enamide (CAS 1240732-77-7)
- 6-Methyl-8-oxo-7,8-dihydroimidazo[1,5-a]pyrazine-1-carboxylic acid (CAS 1708428-08-3)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com