3-Chloro-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid CAS 900014-87-1

Purity 97%+In StockPharmaceutical Standards
CAS No.900014-87-1
Molecular FormulaC8H4ClIN2O2
Molecular Weight322.49 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid CAS 900014-87-1 chemical structure

Description

The occurrence of 3-Chloro-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-Chloro-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 900014-87-1) is a high-purity analytical reference standard with the molecular formula C8H4ClIN2O2 and a molecular weight of 322.49 g/mol.

3-Chloro-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid (C8H4ClIN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Chloro-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H4ClIN2O2
Molecular Weight322.49 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl/I-containing
Nitrogen Atoms2

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