3-{2-[(2-Fluorobenzoyl)amino]phenoxy}-2-thiophenecarboxylic acid CAS 900019-03-6
| CAS No. | 900019-03-6 |
| Molecular Formula | C18H12FNO4S |
| Molecular Weight | 357.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-{2-[(2-Fluorobenzoyl)amino]phenoxy}-2-thiophenecarboxylic acid is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-{2-[(2-Fluorobenzoyl)amino]phenoxy}-2-thiophenecarboxylic acid (CAS 900019-03-6), molecular formula C18H12FNO4S and molecular weight 357.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-{2-[(2-Fluorobenzoyl)amino]phenoxy}-2-thiophenecarboxylic acid (C18H12FNO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-{2-[(2-Fluorobenzoyl)amino]phenoxy}-2-thiophenecarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H12FNO4S |
| Molecular Weight | 357.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorobenzoyl Standards
- 3-(3-(2-Fluorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide (CAS 858118-87-3)
- 4-(3-(2-Fluorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide (CAS 858118-63-5)
- 4-(3-(2-Fluorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide (CAS 858118-29-3)
- 1-(9-Ethyl-6-(4-fluorobenzoyl)-9H-carbazol-3-yl)ethanone (CAS 876907-97-0)
- 4-(4-Fluorobenzoyl)-N-[3-(morpholin-4-yl)propyl]-1H-pyrrole-2-carboxamide (CAS 439111-51-0)
- 3-(4-Fluorobenzoyl)-4-(4-methylphenyl)-1-phenylpyrrolidine (CAS 551921-55-2)
- 3-(1-(4-Fluorobenzoyl)-1H-pyrazol-3-yl)-1-phenylpyridazin-4(1H)-one (CAS 318497-98-2)
- 6-(4-Fluorobenzoyl)-7-thia-1,9-diazatetracyclo[9.2.2.0^{2,10}.0^{4,8}]pentadeca-2(10),3,5,8-tetraen-5-amine (CAS 939888-43-4)
Recommended Standards
- 3,3',3''-(1,3,5-Triazine-2,4,6-triyl)triphenol (CAS 2225834-22-8)
- 4-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)methylene)-2-(naphthalen-1-yl)oxazol-5(4H)-one (CAS 379250-05-2)
- 3-(4-(2-Fluorobenzamido)phenoxy)thiophene-2-carboxylic acid (CAS 900015-24-9)
- 4-(3-(3-Hydroxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide (CAS 858118-39-5)
- 3,3-Dimethylindolin-6-ol (CAS 87234-89-7)
- 2-Acetylbenzo[d]oxazole-7-carbonitrile (CAS 1520034-59-6)
- 5-Hydroxy-4-(pyridin-3-yl)isoquinolin-1(2H)-one (CAS 656234-43-4)
- 1-(3-Fluoro-4-methylphenyl)ethanamine hydrochloride (CAS 2138165-91-8)
- 2-(4-Nitrobenzyl)malononitrile (CAS 6731-53-9)
- tert-Butyl 4-(4-formylbenzyl)piperazine-1-carboxylate (CAS 844891-09-4)
- (R)-N-Boc-4-(hydroxymethyl)-2,2-dimethyloxazolidine (CAS 108149-63-9)
- (1E,2Z)-3-chloro-3-phenylacrylaldehyde oxime (CAS 72806-43-0)
- 6-Oxo-6-(4-(trifluoromethyl)phenyl)hexanenitrile (CAS 61718-88-5)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com