2-Methyl-5-(trifluoromethoxy)-1H-indole CAS 900182-99-2
| CAS No. | 900182-99-2 |
| Molecular Formula | C10H8F3NO |
| Molecular Weight | 215.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Methyl-5-(trifluoromethoxy)-1H-indole.
2-Methyl-5-(trifluoromethoxy)-1H-indole (CAS 900182-99-2) is a high-purity analytical reference standard with the molecular formula C10H8F3NO and a molecular weight of 215.17 g/mol.
The molecular framework of 2-Methyl-5-(trifluoromethoxy)-1H-indole (C10H8F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Methyl-5-(trifluoromethoxy)-1H-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F3NO |
| Molecular Weight | 215.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-(2-Methyl-5-(trifluoromethoxy)phenyl)acetonitrile (CAS 1261683-78-6)
- 2-(2-Methyl-4-(trifluoromethoxy)phenyl)acetonitrile (CAS 886763-09-3)
- 2-(3-Methyl-5-(trifluoromethoxy)phenyl)acetonitrile (CAS 916420-56-9)
- 2-Methyl-6-(trifluoromethoxy)-1H-indole (CAS 57330-49-1)
- 3-(Trifluoromethoxy)benzoyl cyanide (CAS 80277-37-8)
- 4-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-one (CAS 1083090-91-8)
- 3-(3-(Trifluoromethoxy)phenyl)prop-2-yn-1-ol (CAS 1093173-10-4)
- 3-(2-(Trifluoromethoxy)phenyl)prop-2-yn-1-ol (CAS 1141049-59-3)
Recommended Standards
- 2,2,2-Trifluoro-1-(isoindolin-2-yl)ethan-1-one (CAS 832-51-9)
- 2-(Trifluoromethyl)-7,8-dihydroquinolin-6(5H)-one (CAS 944895-70-9)
- 3-(3-Cyanophenyl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 944905-77-5)
- 2-(Trifluoromethyl)-7,8-dihydroquinolin-5(6H)-one (CAS 890301-86-7)
- (E)-4-(3-bromobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one (CAS 1142199-51-6)
- 5-(Piperidine-1-sulfonyl)pyridin-2-amine (CAS 627839-20-7)
- 1H-Indole-2,4-dicarboxylic acid (CAS 103027-96-9)
- Pyridostigmine Impurity 2 (CAS 4685-07-8(free base))
- 6-Amino-1H-indole-4-carboxylic acid (CAS 885520-34-3)
- Ethyl N-[2-cyano-3-(4-methoxyanilino)acryloyl]carbamate (CAS 75837-80-8)
- 4-Bromo-6-chloro-1H-indazol-3-amine (CAS 1936397-29-3)
- 7-Methyl-3,5-dihydrospiro[benzo[b]azepine-4,2'-[1,3]dioxolan]-2(1H)-one (CAS 2677030-95-2)
- 5-Bromo-3-fluoro-2-methoxybenzene-1-sulfonyl chloride (CAS 612541-19-2)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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