3-(2-Chlorophenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine CAS 900286-98-8
| CAS No. | 900286-98-8 |
| Molecular Formula | C20H24ClN5O |
| Molecular Weight | 385.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2-Chlorophenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(2-Chlorophenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 900286-98-8) is a high-purity analytical reference standard with the molecular formula C20H24ClN5O and a molecular weight of 385.89 g/mol.
The molecular framework of 3-(2-Chlorophenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine (C20H24ClN5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chlorophenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24ClN5O |
| Molecular Weight | 385.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chlorophenyl Standards
- 2-[4-(3-Chlorophenyl)piperazin-1-yl]-N-(3,4-dihydro-2H-1-benzopyran-4-yl)acetamide (CAS 1147359-04-3)
- 4-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-N-(4-methyl-1,3-thiazol-2-yl)pyrimidin-2-amine (CAS 1823183-28-3)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-5-(2-phenyl-1,3-thiazol-4-yl)-1,3,4-oxadiazole (CAS 338760-61-5)
- 3-(4-Chlorophenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 849910-86-7)
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-phenylcarbamate (CAS 477872-50-7)
- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethan-1-one (CAS 332161-42-9)
- Ethyl 5-((4-chlorophenyl)thio)-3-(p-tolyl)-1,2,4-triazine-6-carboxylate (CAS 338965-80-3)
- Ethyl 5-[(2-chlorophenyl)sulfanyl]-3-(4-methylphenyl)-1,2,4-triazine-6-carboxylate (CAS 338965-78-9)
Recommended Standards
- 1-[(5-chlorothien-2-yl)sulfonyl]-4-phenylpiperidine-4-carboxylic acid (CAS 851619-66-4)
- 3-Amino-N-(3-chlorophenyl)-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 487039-35-0)
- N2-((1R,2S)-2-Aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine (CAS 190653-73-7)
- 6-((6-Chloro-2-methoxyacridin-9-yl)amino)-N-methylhexanamide (CAS 77431-60-8)
- [(5-methylfuran-2-yl)methyl](pentan-3-yl)amine (CAS 937664-07-8)
- 1-(1-Iodoethenyl)-4-methylbenzene (CAS 359887-53-9)
- 2-Heptyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 872531-12-9)
- 2-((5-(Pyridin-2-yl)-1,3,4-oxadiazol-2-yl)thio)propanamide (CAS 604739-85-7)
- Boc-D-β-Homo-Tyr(OBzl)-OH (CAS 1858273-56-9)
- 2-(4-Aminophenyl)-6-(difluoromethyl)pyrimidin-4(3h)-one (CAS 1498572-89-6)
- 2,3,4,9-Tetrahydro-1H-carbazol-7-ol (CAS 13314-79-9)
- Methyl 6-((methylsulfonyl)methyl)nicotinate (CAS 597562-53-3)
- N-(4-Hydroxy-2-isopropoxyphenyl)methanesulfonamide (CAS 1243470-95-2)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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