5,7-Difluoro-2-(4-fluorophenyl)-1h-indole CAS 901188-04-3
| CAS No. | 901188-04-3 |
| Molecular Formula | C14H8F3N |
| Molecular Weight | 247.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5,7-Difluoro-2-(4-fluorophenyl)-1h-indole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5,7-Difluoro-2-(4-fluorophenyl)-1h-indole (CAS 901188-04-3), a certified reference material (molecular formula C14H8F3N, MW 247.22 g/mol) for analytical method development and quality control.
The molecular framework of 5,7-Difluoro-2-(4-fluorophenyl)-1h-indole (C14H8F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5,7-Difluoro-2-(4-fluorophenyl)-1h-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F3N |
| Molecular Weight | 247.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- ethyl 5,5-difluoro-4-oxo-6,7-dihydro-1H-indole-2-carboxylate (CAS 1263083-10-8)
- 2,6-Difluoro-N-(m-tolyl)benzamide (CAS 878077-35-1)
- 2,6-Difluoro-N-(o-tolyl)benzamide (CAS 418793-07-4)
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- 2,6-Difluoro-4-(4-vinylcyclohexyl)benzonitrile (CAS 337366-98-0)
- methyl 2,2-difluoro-2-(quinolin-6-yl)acetate (CAS 943541-38-6)
- 2,3-Difluoro-5-nitrophenyl ethyl carbonate (CAS 1235492-42-8)
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Recommended Standards
- 4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide (CAS 88353-01-9)
- 6-(5-fluoro-2-methoxyphenyl)pyridine-2-carboxylic acid (CAS 887982-75-4)
- 4-Fluoro-N-(2-(furan-2-yl)-2-oxoethyl)benzamide (CAS 88352-93-6)
- 6-[(2-fluorophenyl)methoxy]pyridine-3-carboxylic acid (CAS 438049-63-9)
- Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate (CAS 343864-83-5)
- (6-(Cyclohexylamino)pyridin-2-yl)boronic acid (CAS 1310384-86-1)
- trans-5-(tert-butoxycarbonylamino)tetrahydropyran-2-carboxylic acid (CAS 2411503-41-6)
- 5-Bromo-3-hydroxy-2,3-dihydrobenzothiophene 1,1-Dioxide (CAS 1428725-91-0)
- Oseltamivir Impurity 172 (CAS CATO-C4X-1720172)
- Ilaprazole Impurity 160 (CAS CATO-C4X-1130160)
- 3-(1-Butyl-3,5-dimethyl-1h-pyrazol-4-yl)-1h-pyrazole-5-carboxylic acid (CAS 890624-27-8)
- N-(3-Iodo-4-methylphenyl)thiophene-3-amide (CAS 623907-55-1)
- 3,4-Bis(4-methoxybenzoyl)-1,2,5-oxadiazole 2-oxide (CAS 40499-78-3)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
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