3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine-6-thiol CAS 901273-03-8

Description

Compared with other compounds in its class, the molecular weight of 272.41 g/mol gives 3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine-6-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine-6-thiol (CAS 901273-03-8) is a high-purity analytical reference standard with the molecular formula C12H24N4OS and a molecular weight of 272.41 g/mol.

The molecular framework of 3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine-6-thiol (C12H24N4OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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