Ethyl 4-methyl-2-(4-phenylpiperazin-1-yl)pyrimidine-5-carboxylate CAS 903446-60-6
| CAS No. | 903446-60-6 |
| Molecular Formula | C18H22N4O2 |
| Molecular Weight | 326.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 4-methyl-2-(4-phenylpiperazin-1-yl)pyrimidine-5-carboxylate (C18H22N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ethyl 4-methyl-2-(4-phenylpiperazin-1-yl)pyrimidine-5-carboxylate (CAS 903446-60-6) is a high-purity analytical reference standard with the molecular formula C18H22N4O2 and a molecular weight of 326.39 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22N4O2 |
| Molecular Weight | 326.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Recommended Standards
- Ethyl 4-(2-(naphthalen-2-yl)acetyl)piperazine-1-carboxylate (CAS 694498-72-1)
- Furan-2-yl(2-(pyrimidin-2-yl)-2,9-diazaspiro[5.5]undecan-9-yl)methanone (CAS 959559-79-6)
- Ethyl 2-(benzo[b]thiophen-3-yl)acetate (CAS 7597-68-4)
- Furan-2-yl(9-(pyrimidin-2-yl)-3,9-diazaspiro[5.5]undecan-3-yl)methanone (CAS 959503-71-0)
- 4-Hydroxy-3-[3-(4-hydroxyphenyl)acryloyl]-6-methyl-2H-pyran-2-one (CAS 14006-18-9)
- 2-Methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carbohydrazide (CAS 145888-70-6)
- 3-Methoxy-N,N-dimethylpropan-1-amine hydrochloride (CAS 2126176-93-8)
- Ethyl 2-methyl-6-oxocyclohex-1-ene-1-carboxylate (CAS 89337-63-3)
- 2-Octyldodecan-1-amine (CAS 62281-06-5)
- 2,4-Dioxo-3-phenyl-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid (CAS 669752-01-6)
- ((Tetrahydro-2H-pyran-2-yl)methyl)hydrazine (CAS 1154975-34-4)
- 2-[(propan-2-yl)sulfamoyl]benzoic acid (CAS 790247-43-7)
- endo-BCN-PEG2-alcohol (CAS 1807501-85-4)
- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com