4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine CAS 90358-16-0
| CAS No. | 90358-16-0 |
| Molecular Formula | C7H15ClN4 |
| Molecular Weight | 190.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 90358-16-0), a certified reference material (molecular formula C7H15ClN4, MW 190.67 g/mol) for analytical method development and quality control.
The molecular framework of 4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (C7H15ClN4) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H15ClN4 |
| Molecular Weight | 190.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 6-chloro-3-methylimidazo[1,2-b]pyridazin-2-amine (CAS 1005785-59-0)
- (4-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)methanol (CAS 1015610-07-7)
- 5-Chloro-4-methoxy-1H-pyrrolo[2,3-b]pyridine (CAS 1020056-69-2)
- 4-Chloro-5-methoxy-1H-pyrrolo[2,3-b]pyridine (CAS 1020056-72-7)
- 8-chloro-1,5-naphthyridin-3-ol (CAS 1071541-08-6)
- 2-Chloro-N-(1-methylpiperidin-4-yl)acetamide (CAS 1096305-49-5)
- (R)-2-Chloro-1-(3-(dimethylamino)pyrrolidin-1-yl)ethanone (CAS 1107645-69-1)
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Recommended Standards
- 4-chloro-2,6-dimethylfuro[2,3-d]pyrimidine (CAS 25716-58-9)
- 4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 204929-06-6)
- 4-chloro-1,3-dimethyl-pyrazolo[3,4-d]pyrimidine (CAS 87412-89-3)
- 4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 90065-71-7)
- 2-Amino-7-(difluoromethyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 1706441-54-4)
- 1-(2-Bromophenyl)-3-fluoropropan-1-one (CAS 1245806-55-6)
- 2-((4,6-Dimethoxy-1,3,5-triazin-2-yl)(methyl)amino)ethanol (CAS 52298-77-8)
- (R)-5-Amino-4-methylpentan-1-ol hydrochloride (CAS 2734714-91-9)
- {2-[(2-chlorophenyl)sulfanyl]pyridin-3-yl}methyl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 339278-60-3)
- (1-Ethyl-5-methyl-1h-pyrazol-4-yl)methanamine (CAS 898046-26-9)
- 2-(3,3-Dimethylcyclohexyl)-2-hydroxyacetic acid (CAS 1508483-13-3)
- 2-(1H-Imidazol-1-yl)-5-phenyl-1,3,4-thiadiazole (CAS 203389-73-5)
- 4,4'-(Decane-1,1-diyl)diphenol (CAS 61593-21-3)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
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