N-{5-[2-chloro-5-(trifluoromethyl)phenyl]pyrazin-2-yl}-2,6-difluorobenzamide CAS 903591-53-7
| CAS No. | 903591-53-7 |
| Molecular Formula | C18H9ClF5N3O |
| Molecular Weight | 413.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures N-{5-[2-chloro-5-(trifluoromethyl)phenyl]pyrazin-2-yl}-2,6-difluorobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies N-{5-[2-chloro-5-(trifluoromethyl)phenyl]pyrazin-2-yl}-2,6-difluorobenzamide (CAS 903591-53-7), a certified reference material (molecular formula C18H9ClF5N3O, MW 413.73 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-{5-[2-chloro-5-(trifluoromethyl)phenyl]pyrazin-2-yl}-2,6-difluorobenzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 413.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H9ClF5N3O |
| Molecular Weight | 413.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 4-chloro-3-iodo-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[4,3-c]pyridine (CAS 1246349-97-2)
- Chloro[1,3-bis(t-butyl)-2H-imidazol-2-ylidene]gold(I) (CAS 839722-07-5)
- 1-[1-(3-Chloro-4-fluorophenyl)-1H-1,2,3-triazol-4-yl]-2-[3-(trifluoromethyl)phenoxy]propan-1-one (CAS 1797898-47-5)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-3-(4-fluorobenzyl)-4-hydroxypyridin-2(1H)-one (CAS 478247-90-4)
- 2-Chloro-9-isopropyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-9H-purin-6-amine (CAS 1056016-74-0)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(2-(trifluoromethyl)phenyl)thiourea (CAS 326815-15-0)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(3-(trifluoromethyl)phenyl)thiourea (CAS 326815-25-2)
- Ethyl 2-(3-chloro-2-oxo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trimethylsilyl)pyridin-1(2H)-yl)acetate (CAS 1417647-15-4)
Recommended Standards
- (E)-2-(4-chlorostyryl)-1-(3,4-dichlorobenzyl)-1H-benzo[d]imidazole (CAS 306977-79-7)
- N1-[3-(2,3,4,5,6-pentafluorophenoxy)phenyl]-2-chlorobenzamide (CAS 331632-61-2)
- (E)-2-(2-chlorostyryl)-1-(2,6-dichlorobenzyl)-1H-benzo[d]imidazole (CAS 338772-15-9)
- N1-[3-(2,3,4,5,6-pentafluorophenoxy)phenyl]-4-chlorobenzamide (CAS 331632-62-3)
- 1-(Cycloheptylamino)-2-methylpropan-2-ol (CAS 1179109-45-5)
- methyl 5-amino-1-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 1630907-29-7)
- 3-Bromo-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 1251249-98-5)
- 2-(Tert-butylamino)-N-(3,5-difluorophenyl)acetamide (CAS 1090033-18-3)
- 5-Cyclopropoxy-6-isopropoxynicotinamide (CAS 1243353-57-2)
- rac-(1r,4r)-4-(3-methylbutoxy)cyclohexan-1-amine hydrochloride (CAS 2031242-58-5)
- 1,3-BIs(1,1-dimethylethyl) 2-(3-bromopropyl)imidodicarbonate (CAS 172846-33-2)
- (S)-1-Amino-2,3-dihydro-1H-indene-5-carboxylic acid (CAS 903630-36-4)
- Methyl 2-amino-3-tert-butylbenzoate (CAS 1343059-55-1)
- MLCK inhibitor peptide 18 (CAS 224579-74-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com