3-[(4-Aminophenyl)thio]-1-(4-iodophenyl)pyrrolidine-2,5-dione CAS 903777-35-5
| CAS No. | 903777-35-5 |
| Molecular Formula | C16H13IN2O2S |
| Molecular Weight | 424.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-[(4-Aminophenyl)thio]-1-(4-iodophenyl)pyrrolidine-2,5-dione (CAS 903777-35-5) is a high-purity analytical reference standard with the molecular formula C16H13IN2O2S and a molecular weight of 424.26 g/mol.
The molecular framework of 3-[(4-Aminophenyl)thio]-1-(4-iodophenyl)pyrrolidine-2,5-dione (C16H13IN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13IN2O2S |
| Molecular Weight | 424.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (cis-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl methyl sulfate (CAS 1992946-35-6)
- 3-Amino-N-(2-bromo-4,6-difluorophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 497061-48-0)
- 8-Bromo-1-cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-35-5)
- N-(3-bromo-5-oxo-4-phenoxy-2,5-dihydrofuran-2-yl)-2-methylbenzenesulfonamide (CAS 126956-35-2)
- 4-Nitro-1-(propan-2-yl)-1h-imidazole (CAS 866251-86-7)
- Isobutyl 2-(3-oxopiperazin-2-yl)acetate (CAS 1025496-29-0)
- 4-(Piperazin-1-yl)-7-(trifluoromethyl)quinoline (CAS 104668-02-2)
- 2-Chloro-2-methyltetrahydro-2H-pyran (CAS 89357-26-6)
- 5-Bromo-2-chloro-N-(5-methylpyridin-2-yl)benzamide (CAS 923779-05-9)
- 2-(2-(5-Bromo-2-fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443354-87-7)
- N1-(2-fluorobenzyl)ethane-1,2-diamine (CAS 953072-16-7)
- 3,3'-Oxydianiline (CAS 15268-07-2)
- Tert-butyl 4-(5-fluoro-2-methylphenyl)-3-hydroxypiperidine-1-carboxylate (CAS 1354953-20-0)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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