N-Methyl-3,5-difluorobenzylamine Hydrochloride CAS 90389-29-0
| CAS No. | 90389-29-0 |
| Molecular Formula | C8H9F2N |
| Molecular Weight | 157.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-Methyl-3,5-difluorobenzylamine Hydrochloride (C8H9F2N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies N-Methyl-3,5-difluorobenzylamine Hydrochloride (CAS 90389-29-0), a certified reference material (molecular formula C8H9F2N, MW 157.16 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9F2N |
| Molecular Weight | 157.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- N-Methyl-2,3-difluorobenzylamine (CAS 906645-41-8)
- 6-Methyl-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1000340-62-4)
- N1,N1-dimethyl-2,6-difluoroaniline (CAS 55847-15-9)
- 6-Methyl-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile (CAS 1000340-86-2)
- 2-Chloro-3-(5-ethoxycarbonyl-2-thenoyl)pyridine (CAS 890100-49-9)
- 7-Methoxy-3-(thiophen-2-yl)isobenzofuran-1(3H)-one (CAS 91362-88-8)
- Tert-butyl ((benzyloxy)carbonyl)-L-phenylalaninate (CAS 7670-20-4)
- Plicatol B (CAS 108335-06-4)
- LABD-8(17),14-dien-13,19-diol (CAS 3650-30-4)
- 2-Methyl-2H-indazole-7-sulfonyl chloride (CAS 1363380-68-0)
- n-(2-Chlorobenzyl)-2-(ethylsulfonyl)ethan-1-amine (CAS 1157829-73-6)
- 1,5-bis(3,4-dichlorophenyl)penta-1,4-dien-3-one (CAS 42160-05-4)
- Itraconazole Impurity 82 (CAS CATO-C4X-149782)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
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