Methyl 3-(4-bromo-1-tosyl-1H-indol-3-yl)acrylate CAS 90481-80-4
| CAS No. | 90481-80-4 |
| Molecular Formula | C19H16BrNO4S |
| Molecular Weight | 434.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Methyl 3-(4-bromo-1-tosyl-1H-indol-3-yl)acrylate (CAS 90481-80-4), molecular formula C19H16BrNO4S and molecular weight 434.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 3-(4-bromo-1-tosyl-1H-indol-3-yl)acrylate (C19H16BrNO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16BrNO4S |
| Molecular Weight | 434.30 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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- 5-Mercapto-4-(p-tolyl)-4H-1,2,4-triazol-3-ol (CAS 39186-15-7)
- tert-Butyl 2-bromo-4-((tert-butoxycarbonyl)amino)nicotinate (CAS 1044148-94-8)
- Bexarotene Impurity 4 (CAS CATO-C4X-29494)
- Guanoxan-d4 (CAS 1794783-67-7)
- 2-(6-Chloropyridin-2-yl)-N-methylhydrazine-1-carboxamide (CAS 353259-45-7)
- 3-Fluoro-4-(thiomorpholinomethyl)benzaldehyde (CAS 1443338-40-6)
- Methyl perfluorononanoate (CAS 51502-45-5)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
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