Fluticasone CAS 90566-53-3
| CAS No. | 90566-53-3 |
| Molecular Formula | C22H27F3O4S |
| Molecular Weight | 444.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 444.51 g/mol gives Fluticasone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Fluticasone (CAS 90566-53-3) is a high-purity analytical reference standard with the molecular formula C22H27F3O4S and a molecular weight of 444.51 g/mol.
Fluticasone (C22H27F3O4S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Fluticasone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27F3O4S |
| Molecular Weight | 444.51 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Related Compound B (CAS 219719-95-6)
- Fluticasone Impurity 51 (CAS CATO-C4X-165051)
- Fluticasone Impurity 76 (CAS CATO-C4X-165076)
- Fluticasone Impurity 79 (CAS CATO-C4X-165079)
- Fluticasone Impurity 102 (CAS CATO-C4X-1650102)
- Fluticasone Propionate EP Impurity A (CAS 65429-42-7)
- Fluticasone Impurity 84 (CAS CATO-C4X-165084)
- Fluticasone Impurity 83 (CAS CATO-C4X-165083)
Recommended Standards
- 7,7-Dimethyl-1-[({4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}sulfonyl)methyl]bicyclo[2.2.1]heptan-2-one (CAS 315692-83-2)
- N-[2-(1H-Indol-3-yl)ethyl]-4-methyl-7-[(2-methyl-2-propen-1-yl)oxy]-2-oxo-2H-1-benzopyran-6-propanamide (CAS 1010871-55-2)
- N-(5-(1,3-Dimethyl-1H-pyrazol-5-yl)-1,3,4-oxadiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide (CAS 1170648-89-1)
- 2,2′-[1,1′:3′,1′′:3′′,1′′′-Quaterphenyl]-2′,2′′-diylbis[4,5-dihydrooxazole] (CAS 1021602-62-9)
- N-(Pyrazolo[1,5-a]pyridin-3-ylmethyl)-1-naphthamide (CAS 1396707-20-2)
- 6H-Indolo[2,3-b]quinoxaline (CAS 243-59-4)
- N-(1-(5-Formylthiophen-2-yl)propan-2-yl)-4-methylbenzenesulfonamide (CAS 1170097-60-5)
- 2-Chloro-5-nitroisonicotinamide (CAS 1224637-08-4)
- 2-(Ethylthio)-1-(3-fluoro-4-methoxyphenyl)ethan-1-one (CAS 1157221-25-4)
- Ethyl 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate (CAS 132214-26-7)
- 5-Chloro-1-phenyl-1H-tetrazole (CAS 14210-25-4)
- 1-(3-Chloro-4-fluorophenyl)pyrrolidine (CAS 1000339-33-2)
- 6-(3-Hydroxyprop-1-yn-1-yl)-1-(4-methoxybenzyl)-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 1198425-67-0)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
Why CATO?
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